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中文名稱:人MYC重組蛋白
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貨號(hào):CSB-EP015270HU
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說(shuō)明書(shū):
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規(guī)格:¥1344
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圖片:
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其他:
產(chǎn)品詳情
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純度:Greater than 90% as determined by SDS-PAGE.
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基因名:
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Uniprot No.:
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別名:AU016757; Avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; Cellular myelocytomatosis oncogene; Class E basic helix-loop-helix protein 39; MGC105490; MRTL; Myc; Myc protein; Myc proto oncogene protein; Myc proto-oncogene protein; myc-related translation/localization regulatory factor; MYC_HUMAN; Myc2; myca; MYCC; Myelocytomatosis oncogene a; Myelocytomatosis oncogene; Niard; Nird; oncogene c-Myc; Oncogene Myc; OTTHUMP00000158589; OTTHUMP00000227763; Proto-oncogene c-Myc; Protooncogene homologous to myelocytomatosis virus; RNCMYC; Transcription factor p64; Transcriptional regulator Myc-A; V-Myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog (avian); zc-myc
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種屬:Homo sapiens (Human)
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蛋白長(zhǎng)度:Full Length of Isoform 1
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來(lái)源:E.coli
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分子量:52.8 kDa
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表達(dá)區(qū)域:1-439
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氨基酸序列MPLNVSFTNR NYDLDYDSVQ PYFYCDEEEN FYQQQQQSEL QPPAPSEDIW KKFELLPTPP LSPSRRSGLC SPSYVAVTPF SLRGDNDGGG GSFSTADQLE MVTELLGGDM VNQSFICDPD DETFIKNIII QDCMWSGFSA AAKLVSEKLA SYQAARKDSG SPNPARGHSV CSTSSLYLQD LSAAASECID PSVVFPYPLN DSSSPKSCAS QDSSAFSPSS DSLLSSTESS PQGSPEPLVL HEETPPTTSS DSEEEQEDEE EIDVVSVEKR QAPGKRSESG SPSAGGHSKP PHSPLVLKRC HVSTHQHNYA APPSTRKDYP AAKRVKLDSV RVLRQISNNR KCTSPRSSDT EENVKRRTHN VLERQRRNEL KRSFFALRDQ IPELENNEKA PKVVILKKAT AYILSVQAEE QKLISEEDLL RKRREQLKHK LEQLRNSCA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering. -
蛋白標(biāo)簽:N-terminal 6xHis-tagged
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產(chǎn)品提供形式:Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
緩沖液:If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose. -
儲(chǔ)存條件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質(zhì)期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期:3-7 business days
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注意事項(xiàng):Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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產(chǎn)品描述:Recombinant Human Myc proto-oncogene protein (MYC)是一種重組的人源性MYC原癌基因蛋白。MYC屬于轉(zhuǎn)錄因子家族,是細(xì)胞增殖和分化調(diào)控的重要調(diào)節(jié)因子之一。它在細(xì)胞周期調(diào)節(jié)、細(xì)胞生長(zhǎng)和凋亡等生物過(guò)程中發(fā)揮關(guān)鍵作用。MYC蛋白在正常生理?xiàng)l件下表達(dá)水平相對(duì)較低,但在某些腫瘤細(xì)胞中常表現(xiàn)出過(guò)度表達(dá)。研究發(fā)現(xiàn),MYC的過(guò)度表達(dá)會(huì)導(dǎo)致細(xì)胞增殖的異常和癌癥的發(fā)生。因此,對(duì)MYC的研究對(duì)于深入了解癌癥的發(fā)生機(jī)制以及開(kāi)發(fā)相應(yīng)的治療方法具有重要意義。華美生物的MYC重組蛋白是由大腸桿菌表達(dá)系統(tǒng)表達(dá)的全長(zhǎng)重組蛋白,可以廣泛應(yīng)用于生物醫(yī)學(xué)研究,如癌癥研究、細(xì)胞生物學(xué)和分子生物學(xué)實(shí)驗(yàn)中。利用重組MYC蛋白,研究人員能夠探究其在細(xì)胞增殖和凋亡調(diào)控中的作用機(jī)制,進(jìn)一步闡明癌癥發(fā)生和發(fā)展的分子機(jī)制。
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Datasheet & COA:Please contact us to get it.
引用文獻(xiàn)
- Multitarget mechanism of MYC inhibition by the bacterial lon protease in disease I Ambite, MLY Wan, HT Tran, A Nazari, A Chaudhuri,Scientific Reports,2025
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