Recombinant Human Methionyl-tRNA formyltransferase, mitochondrial (MTFMT), partial

中文名稱：

人MTFMT重組蛋白
貨號：

CSB-YP836198HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人MTFMT重組蛋白
貨號：

CSB-EP836198HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人MTFMT重組蛋白
貨號：

CSB-EP836198HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人MTFMT重組蛋白
貨號：

CSB-BP836198HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人MTFMT重組蛋白
貨號：

CSB-MP836198HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

MTFMT
Uniprot No.：

Q96DP5
別名：

FMT; FMT_HUMAN; FMT1; Methionyl tRNA formyltransferase; mitochondrial; Methionyl-tRNA formyltransferase; mitochondrial; mitochondrial methionyl tRNA formyltransferase; MtFMT
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
表達區(qū)域：

-
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechanism.
基因功能參考文獻：
1. Data indicate that methionyl-tRNA formyltransferase (MTF) mutation initiated poor formylation of mitochondrial methionyl-tRNA and thereby reduced mitochondrial translation efficiency, causing Leigh syndrome. PMID: 25288793
2. We provide detailed clinical descriptions on eleven MTFMT patients and review five previously reported cases PMID: 24461907
3. Recessive mutations in MTFMT underlie defects of the mitochondrial respiratory chain, leading to multi-system disease that includes Leigh syndrome. This paper reports on the biochemical activity of such mutant alleles. PMID: 25288793
4. Mutations in MTFMT underlie a human disorder of formylation causing impaired mitochondrial translation. PMID: 21907147
相關(guān)疾病：

Combined oxidative phosphorylation deficiency 15 (COXPD15); Leigh syndrome (LS)
亞細胞定位：

Mitochondrion.
蛋白家族：

Fmt family
數(shù)據(jù)庫鏈接：

HGNC: 29666

OMIM: 256000

KEGG: hsa:123263

STRING: 9606.ENSP00000220058

UniGene: Hs.531615