Recombinant Human KDEL motif-containing protein 1 (KDELC1)

中文名稱：

人KDELC1重組蛋白
貨號：

CSB-YP764933HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人KDELC1重組蛋白
貨號：

CSB-EP764933HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人KDELC1重組蛋白
貨號：

CSB-EP764933HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人KDELC1重組蛋白
貨號：

CSB-BP764933HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人KDELC1重組蛋白
貨號：

CSB-MP764933HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

KDELC1
Uniprot No.：

Q6UW63
別名：

POGLUT2; EP58; KDELC1; UNQ1910/PRO4357; Protein O-glucosyltransferase 2; EC 2.4.1.-; Endoplasmic reticulum resident protein 58; ER protein 58; ERp58; KDEL motif-containing protein 1; Protein O-xylosyltransferase POGLUT2; EC 2.4.2.-
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

20-502
氨基酸序列

E TGGERQLSPE KSEIWGPGLK ADVVLPARYF YIQAVDTSGN KFTSSPGEKV FQVKVSAPEE QFTRVGVQVL DRKDGSFIVR YRMYASYKNL KVEIKFQGQH VAKSPYILKG PVYHENCDCP LQDSAAWLRE MNCPETIAQI QRDLAHFPAV DPEKIAVEIP KRFGQRQSLC HYTLKDNKVY IKTHGEHVGF RIFMDAILLS LTRKVKMPDV ELFVNLGDWP LEKKKSNSNI HPIFSWCGST DSKDIVMPTY DLTDSVLETM GRVSLDMMSV QANTGPPWES KNSTAVWRGR DSRKERLELV KLSRKHPELI DAAFTNFFFF KHDENLYGPI VKHISFFDFF KHKYQINIDG TVAAYRLPYL LVGDSVVLKQ DSIYYEHFYN ELQPWKHYIP VKSNLSDLLE KLKWAKDHDE EAKKIAKAGQ EFARNNLMGD DIFCYYFKLF QEYANLQVSE PQIREGMKRV EPQTEDDLFP CTCHRKKTKD EL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. Can also catalyze the transfer of xylose from UDP-xylose but less efficiently. Specifically targets extracellular EGF repeats of proteins such as NOTCH1 and NOTCH3. May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway.
基因功能參考文獻：
1. Our results suggest that GA733-2-Fc conjugated to ER-retention motif KDEL is a more efficient antigen to prevent tumor growth induced by colorectal carcinoma and minimize an allergic response. PMID: 30249898
2. This paper reports data on mouse Kdelc1 PMID: 11167020
亞細胞定位：

Endoplasmic reticulum lumen.
蛋白家族：

KDELC family
數據庫鏈接：

HGNC: 19350

OMIM: 611613

KEGG: hsa:79070

STRING: 9606.ENSP00000365172

UniGene: Hs.408629