Recombinant Human Iron-sulfur cluster assembly 2 homolog, mitochondrial (ISCA2)

中文名稱：

人ISCA2重組蛋白
貨號：

CSB-YP769773HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人ISCA2重組蛋白
貨號：

CSB-EP769773HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人ISCA2重組蛋白
貨號：

CSB-EP769773HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人ISCA2重組蛋白
貨號：

CSB-BP769773HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人ISCA2重組蛋白
貨號：

CSB-MP769773HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ISCA2
Uniprot No.：

Q86U28
別名：

c14_5557 ; HESB like domain containing 1; HESB like domain containing protein 1 ; HESB-like domain-containing protein 1; iron sulfur cluster assembly 2 homolog (S. cerevisiae); Iron sulfur cluster assembly 2 homolog; mitochondrial ; Iron-sulfur cluster assembly 2 homolog; mitochondrial; ISCA2; ISCA2_HUMAN
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

9-154
氨基酸序列

LT AATQRAVTPW PRGRLLTASL GPQARREASS SSPEAGEGQI RLTDSCVQRL LEITEGSEFL RLQVEGGGCS GFQYKFSLDT VINPDDRVFE QGGARVVVDS DSLAFVKGAQ VDFSQELIRS SFQVLNNPQA QQGCSCGSSF SIKL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly.
基因功能參考文獻：
1. We identified a homoallelic missense founder mutation in ISCA2 leading to mitochondrial depletion and reduced complex I activity as well as decreased ISCA2, ISCA1 and IBA57 expression in fibroblasts. PMID: 25539947
相關疾病：

Multiple mitochondrial dysfunctions syndrome 4 (MMDS4)
亞細胞定位：

Mitochondrion.
蛋白家族：

HesB/IscA family
數據庫鏈接：

HGNC: 19857

OMIM: 615317

KEGG: hsa:122961

STRING: 9606.ENSP00000452007

UniGene: Hs.291079