Recombinant Human Formin-1 (FMN1), partial

中文名稱：

人FMN1重組蛋白
貨號：

CSB-YP715012HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人FMN1重組蛋白
貨號：

CSB-EP715012HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人FMN1重組蛋白
貨號：

CSB-EP715012HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人FMN1重組蛋白
貨號：

CSB-BP715012HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人FMN1重組蛋白
貨號：

CSB-MP715012HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

FMN1
Uniprot No.：

Q68DA7
別名：

FMN1; FMN; LDFormin-1; Limb deformity protein homolog
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Plays a role in the formation of adherens junction and the polymerization of linear actin cables.
基因功能參考文獻：
1. Formin-1 (FMN1) was shown to reside in the nucleus and studies indicate that some formins can shuttle in and out of the nucleus. PMID: 27913680
2. actin arcs populating the medial, lamella-like region of the immunological synapse (IS) arise from linear actin filaments generated by one or more formins present at the IS distal edge. PMID: 27799367
3. Filopodia initiation: focus on the Arp2/3 complex and formins. PMID: 21975549
4. Chromosomal imbalances in the GREM1 FMN1 region in individuals with limb defects are reported here. PMID: 20610440
5. The obtained data indicate the possibility of participation of polymorphism in gene FMN1 in formation of predisposition to prostate cancer. PMID: 20540360
6. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
7. Observational study of gene-disease association. (HuGE Navigator) PMID: 20540360
8. Observational study of gene-disease association. (HuGE Navigator) PMID: 20200978
9. both mammalian Spir proteins, Spir-1 and Spir-2, interact with mammalian Fmn subgroup proteins formin-1 and formin-2 PMID: 19605360
10. Observational study of gene-disease association. (HuGE Navigator) PMID: 19096130
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亞細胞定位：

Nucleus. Cytoplasm. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
蛋白家族：

Formin homology family, Cappuccino subfamily
數據庫鏈接：

HGNC: 3768

OMIM: 136535

KEGG: hsa:342184

STRING: 9606.ENSP00000333950

UniGene: Hs.657649