Recombinant Human E3 ubiquitin-protein ligase RNF167 (RNF167), partial

中文名稱：

人RNF167重組蛋白
貨號：

CSB-YP875686HU1
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人RNF167重組蛋白
貨號：

CSB-EP875686HU1
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人RNF167重組蛋白
貨號：

CSB-EP875686HU1-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人RNF167重組蛋白
貨號：

CSB-BP875686HU1
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人RNF167重組蛋白
貨號：

CSB-MP875686HU1
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

RNF167
Uniprot No.：

Q9H6Y7
別名：

RNF167; LP2254; E3 ubiquitin-protein ligase RNF167; RING finger protein 167; RING-type E3 ubiquitin transferase RNF167; RING105
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
基因功能參考文獻：
1. Data indicate that E3 ubiquitin-protein ligase RNF167 ubiquitinates Arl8B at the lysine residue K141 and reduces the level of the ADP-ribosylation factor-like 8B Arl8B protein. PMID: 27808481
2. Point mutations are characterized in the RING domain of RNF167 and RNF13. PMID: 24387786
3. mutation of the Godzilla ubiquitylation target lysines on VAMP3 abrogates the formation of enlarged endosomes induced by either Godzilla or RNF167. PMID: 23353890
4. RNF167 is a selective regulator of AMPAR-mediated neurotransmission. PMID: 23129617
亞細胞定位：

Endomembrane system; Single-pass membrane protein. Note=Targeted to cytoplasmic membranes.
組織特異性：

Strongly expressed in the kidney and liver (at protein level).
數據庫鏈接：

HGNC: 24544

OMIM: 610431

KEGG: hsa:26001

STRING: 9606.ENSP00000262482

UniGene: Hs.7158