Recombinant Human Cytosolic carboxypeptidase 1 (AGTPBP1), partial

中文名稱：

Recombinant Human Cytosolic carboxypeptidase 1(AGTPBP1) ,partial
貨號：

CSB-YP891799HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Cytosolic carboxypeptidase 1(AGTPBP1) ,partial
貨號：

CSB-EP891799HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Cytosolic carboxypeptidase 1(AGTPBP1) ,partial
貨號：

CSB-EP891799HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Cytosolic carboxypeptidase 1(AGTPBP1) ,partial
貨號：

CSB-BP891799HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Cytosolic carboxypeptidase 1(AGTPBP1) ,partial
貨號：

CSB-MP891799HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

AGTPBP1
Uniprot No.：

Q9UPW5
別名：

CCP1; 1700020N17Rik; 2310001G17Rik; 2900054O13Rik; 4930445M19Rik; 5730402G09Rik; AGTPBP 1; AGTPBP1; ATP/GTP binding protein 1; ATP/GTP-binding protein 1; BB114605; Carboxypeptidase tubulin; CBPC1_HUMAN; Cytosolic carboxypeptidase 1; DKFZp686M20191; KIAA1035; MGC90651; mKIAA1035; Nervous system nuclear protein induced by axotomy; Nervous system nuclear protein induced by axotomy protein 1 homolog; nmf243; NNA1; OTTHUMP00000021581; OTTHUMP00000063553; pcd; Purkinje cell degeneration; RP11-30C23.1; Soluble carboxypeptidase; Tubulinyl Tyr carboxypeptidase; Tyrosine carboxypeptidase
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of alpha-tubulin as well as non-tubulin proteins such as MYLK. Involved in KLF4 deglutamylation which promotes KLF4 proteasome-mediated degradation, thereby negatively regulating cell pluripotency maintenance and embryogenesis.
基因功能參考文獻：
1. we identified seven new putative CCP1 substrates, all of them harboring acidic amino acids in their gene-encoded C terminus PMID: 25381060
2. Data indicate that a functional nuclear export signals (NESs) in CCP1 that mediates direct binding to the export receptor CRM1. PMID: 23242554
亞細胞定位：

Cytoplasm. Cytoplasm, cytosol. Nucleus. Mitochondrion.
蛋白家族：

Peptidase M14 family
數據庫鏈接：

HGNC: 17258

OMIM: 606830

KEGG: hsa:23287

STRING: 9606.ENSP00000365251

UniGene: Hs.719980