Recombinant Human Cytokine SCM-1 beta (XCL2)

中文名稱：

人XCL2重組蛋白
貨號：

CSB-YP890656HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人XCL2重組蛋白
貨號：

CSB-EP890656HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人XCL2重組蛋白
貨號：

CSB-EP890656HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人XCL2重組蛋白
貨號：

CSB-BP890656HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人XCL2重組蛋白
貨號：

CSB-MP890656HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

XCL2
Uniprot No.：

Q9UBD3
別名：

XCL2; SCYC2; Cytokine SCM-1 beta; C motif chemokine 2; XC chemokine ligand 2
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

22-114
氨基酸序列

VGSEVSHRR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Chemotactic activity for lymphocytes but not for monocytes or neutrophils.
基因功能參考文獻：
1. XCL2 and CX3CL1 expression in lung cancers and adjacent non-cancerous tissues was detected by quantitative PCR and ELISA. The expression of XCL2 and CX3CL1 increases with increasing degree of malignancy, indicating that both chemokines might be important targets in gene therapy for lung cancer. PMID: 27156946
2. analysis of XCL1 and XCL2, members of the C-chemokine subfamily, in the immune system PMID: 25497737
3. identified 13 ADCC-activated genes. Six gene expression assays including 8 of the 13 genes (CCL3, CCL4/CCL4L1/CCL4L2, CD160, IFNG, NR4A3 and XCL1/XCL2) were analyzed in 127 kidney biopsies PMID: 25449536
4. S1P induced the macrophage-recruiting factor CCL2 expression in NB cells via S1P2, providing new insights into the complicated functions of S1P2 in cancer. PMID: 25092091
5. The G carrier of the -2510A/G promoter polymorphism was found to be associated with primary knee knee osteoarthritis among Koreans. PMID: 17763208
6. Wag31 was found to specifically stimulate XCL2 expression in macrophages PMID: 18618175
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亞細胞定位：

Secreted.
蛋白家族：

Intercrine gamma family
數據庫鏈接：

HGNC: 10646

OMIM: 604828

KEGG: hsa:6846

STRING: 9606.ENSP00000356793

UniGene: Hs.458346