Recombinant Human Coiled-coil domain-containing protein 79 (CCDC79)

中文名稱：

人TERB1重組蛋白
貨號：

CSB-YP822742HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人TERB1重組蛋白
貨號：

CSB-EP822742HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人TERB1重組蛋白
貨號：

CSB-EP822742HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人TERB1重組蛋白
貨號：

CSB-BP822742HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人TERB1重組蛋白
貨號：

CSB-MP822742HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

TERB1
Uniprot No.：

Q8NA31
別名：

TERB1; CCDC79; Telomere repeats-binding bouquet formation protein 1; Coiled-coil domain-containing protein 79
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-727
氨基酸序列

MESEDTKKTQ EMKTDLNLLL ECLKYQMDNA FSQKEALVTI HSICQQNSNA SVYFREIGGL MFVKNLAKSS EHSMVKEAAL YTLGAIAEKN VYCQQTLCTS ELFEDLTWFL SNDSNINLKR MSVYVILVLV SNNRTGQTLV RETGCITVLS RLFRTVISKH ELDLSDKNVF QSYQLWSSVC STLCVCVNNP QNDENQMFCC SLFPHANEWL KNCTTPEIIR PICSFIGLTL ANNTYVQKYF VSVGGLDVLS QVLMQLESDS HETLSSAKLA VVVTKTVDAC IADNPTFGIV LSKYHIVSKL LALLLHESLD SGEKFSIMLT LGHCTEDCEE NQYDLFKNNG LPLMIQALTE SQNEELNKAA TFVLHNCKKI TEKLSLSLGE YPFDENETQQ LKDISVKENN LEEHWRKAKE ILHRIEQLER EGNEEEIQRE NYQDNISSMN ISIQNTWKHL HADRIGRGSK AEDEDKSHSR QLQSYKSHGV MSKACTNDDQ MKTPLKSANP VHACYRESEQ NKTLYKAKSS CNQNLHEETT FEKNFVSQSS DHVFKHPVHI AKNIKQQLPV TDPFTLCSDI INKEVVSFLA TPSCSEMLTY RCSGCIAVEK SLNSRNFSKL LHSCPYQCDR HKVIVEAEDR YKSELRKSLI CNKKILLTPR RRQRLSNEST TPGGIKKRRI RKNFTEEEVN YLFNGVKKMG NHWNSILWSF PFQQGRKAVD LAHKYHKLTK HPTCAAS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the MAJIN-TERB1-TERB2 complex, TERB1 probably mediates association with the shelterin/telosome complex via interaction with TERF1, promoting priming telomeric DNA attachment'. Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex. Also recruits cohesin to telomeres to develop structural rigidity.
亞細胞定位：

Chromosome, telomere. Nucleus inner membrane.
蛋白家族：

TERB1 family
數據庫鏈接：

HGNC: 26675

OMIM: 617332

KEGG: hsa:283847

STRING: 9606.ENSP00000462883

UniGene: Hs.376505