Recombinant Human CKLF-like MARVEL transmembrane domain-containing protein 4 (CMTM4), partial

中文名稱：

Recombinant Human CKLF-like MARVEL transmembrane domain-containing protein 4(CMTM4),partial
貨號：

CSB-YP810316HU1
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human CKLF-like MARVEL transmembrane domain-containing protein 4(CMTM4),partial
貨號：

CSB-EP810316HU1
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human CKLF-like MARVEL transmembrane domain-containing protein 4(CMTM4),partial
貨號：

CSB-EP810316HU1-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human CKLF-like MARVEL transmembrane domain-containing protein 4(CMTM4),partial
貨號：

CSB-BP810316HU1
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human CKLF-like MARVEL transmembrane domain-containing protein 4(CMTM4),partial
貨號：

CSB-MP810316HU1
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

CMTM4
Uniprot No.：

Q8IZR5
別名：

CMTM4; CKLFSF4; CKLF-like MARVEL transmembrane domain-containing protein 4; Chemokine-like factor superfamily member 4
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. May protect PD-L1/CD274 from being polyubiquitinated and targeted for degradation.
基因功能參考文獻：
1. CMTM4 is downregulated and exhibits tumour-suppressor activities in clear cell renal cell carcinoma, and could be exploited as a target for clear cell renal cell carcinoma treatment. PMID: 26474560
2. Data show that CMTM4 might be an important gene involved in cell growth and cell cycle regulation. PMID: 20213316
亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Chemokine-like factor family
組織特異性：

Highly expressed in testis and prostate.
數(shù)據(jù)庫鏈接：

HGNC: 19175

OMIM: 607887

KEGG: hsa:146223

STRING: 9606.ENSP00000333833

UniGene: Hs.643961