Recombinant Human CD2 antigen cytoplasmic tail-binding protein 2 (CD2BP2)

中文名稱：

Recombinant Human CD2 antigen cytoplasmic tail-binding protein 2(CD2BP2)
貨號：

CSB-YP004915HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human CD2 antigen cytoplasmic tail-binding protein 2(CD2BP2)
貨號：

CSB-EP004915HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human CD2 antigen cytoplasmic tail-binding protein 2(CD2BP2)
貨號：

CSB-EP004915HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human CD2 antigen cytoplasmic tail-binding protein 2(CD2BP2)
貨號：

CSB-BP004915HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human CD2 antigen cytoplasmic tail-binding protein 2(CD2BP2)
貨號：

CSB-MP004915HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

CD2BP2
Uniprot No.：

O95400
別名：

CD2 (cytoplasmic tail) binding protein 2 ; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2; CD2B2_HUMAN; Cd2bp2; FWP010; LIN1; Snu40; U5 snRNP 52K protein; U5-52K
種屬：

Homo sapiens (Human)
蛋白長度：

Full length protein
表達區域：

1-341
氨基酸序列

MPKRKVTFQG VGDEEDEDEI IVPKKKLVDP VAGSGGPGSR FKGKHSLDSD EEEDDDDGGS SKYDILASED VEGQEAATLP SEGGVRITPF NLQEEMEEGH FDADGNYFLN RDAQIRDSWL DNIDWVKIRE RPPGQRQASD SEEEDSLGQT SMSAQALLEG LLELLLPRET VAGALRRLGA RGGGKGRKGP GQPSSPQRLD RLSGLADQMV ARGNLGVYQE TRERLAMRLK GLGCQTLGPH NPTPPPSLDM FAEELAEEEL ETPTPTQRGE AESRGDGLVD VMWEYKWENT GDAELYGPFT SAQMQTWVSE GYFPDGVYCR KLDPPGGQFY NSKRIDFDLY T
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly.
基因功能參考文獻：
1. Knockdown of CD2BP2 results in reduced miRNA levels. CD2BP2 stabilizes miRISC and mature miRNAs, maintaining them at levels necessary to properly regulate target gene expression. PMID: 28180320
2. CD2BP2 is the ligand of the membrane-proximal proline-rich tandem repeat of CD2 in detergent-soluble membrane compartments. PMID: 12426371
3. there is a function of the GYF domain of CD2BP2 in mediating protein-protein interactions within the spliceosome PMID: 15105431
4. interaction of CD2BP2 with a tri-snRNP bridging protein (Prp6), coupled with CD2BP2's absence from the tri-snRNP, suggests it might function in tri-snRNP assembly PMID: 15840814
5. findings indicate that CD2BP2 is not a constitutive binding partner or key regulator of CD2-mediated signaling events PMID: 17906334
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亞細胞定位：

Cytoplasm. Nucleus. Note=Predominantly nuclear.
數據庫鏈接：

HGNC: 1656

OMIM: 604470

KEGG: hsa:10421

STRING: 9606.ENSP00000304903

UniGene: Hs.202677