Recombinant Human Band 4.1-like protein 4B (EPB41L4B), partial

中文名稱：

人EPB41L4B重組蛋白
貨號：

CSB-YP872483HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人EPB41L4B重組蛋白
貨號：

CSB-EP872483HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人EPB41L4B重組蛋白
貨號：

CSB-EP872483HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人EPB41L4B重組蛋白
貨號：

CSB-BP872483HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人EPB41L4B重組蛋白
貨號：

CSB-MP872483HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

EPB41L4B
Uniprot No.：

Q9H329
別名：

Band 4.1 like protein 4B; Band 4.1-like protein 4B; CG1; DKFZp761N1814; E41LB_HUMAN; EHM 2; Epb41l4b; Erythrocyte membrane protein band 4.1 like 4B; FERM containing protein; FERM containing protein CG1; FERM-containing protein CG1; FLJ21596; OTTHUMP00000021883; OTTHUMP00000021884; Protein EHM2
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18. Involved in the regulation of the circumferential actomyosin belt in epithelial cells. Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing. May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation.
基因功能參考文獻：
1. CRB3A recruits p114RhoGEF and its activator Ehm2 to the cell periphery using both functional motifs of its cytoplasmic tail and increases RhoA activation levels. PMID: 26217016
2. Ehm2 may be an important player in the wound healing process; Ehm2 knockdown downregulates the expression of NWasp, through which it may have its effect on cellular migration PMID: 23664528
3. (review) FERM domains are found in a wide variety of proteins, but in particular they constitute the major, and in some cases the only, recognized functional domain present in the FRMDs. PMID: 23662806
亞細胞定位：

Cytoplasm. Cell junction, tight junction.
組織特異性：

Expressed at higher levels in acute wounds than chronic wounds with increased expression in healing wounds, especially at the leading wound edge. Isoform 1 is highly expressed in brain. Isoform 2 is highly expressed in testis with lower levels in prostate
數據庫鏈接：

HGNC: 19818

OMIM: 610340

KEGG: hsa:54566

STRING: 9606.ENSP00000363694

UniGene: Hs.591901