Recombinant Human BTB/POZ domain-containing protein KCTD17 (KCTD17)

中文名稱：

人KCTD17重組蛋白
貨號：

CSB-YP850810HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人KCTD17重組蛋白
貨號：

CSB-EP850810HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人KCTD17重組蛋白
貨號：

CSB-EP850810HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人KCTD17重組蛋白
貨號：

CSB-BP850810HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人KCTD17重組蛋白
貨號：

CSB-MP850810HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

KCTD17
Uniprot No.：

Q8N5Z5
別名：

BTB; BTB/POZ domain-containing protein KCTD17; FLJ12242; FLJ98761; KCD17_HUMAN; KCTD17; Potassium channel tetramerisation domain containing 17; POZ domain-containing protein KCTD17; RP5-1170K4.4
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-321
氨基酸序列

MQTPRPAMRM EAGEAAPPAG AGGRAAGGWG KWVRLNVGGT VFLTTRQTLC REQKSFLSRL CQGEELQSDR DETGAYLIDR DPTYFGPILN FLRHGKLVLD KDMAEEGVLE EAEFYNIGPL IRIIKDRMEE KDYTVTQVPP KHVYRVLQCQ EEELTQMVST MSDGWRFEQL VNIGSSYNYG SEDQAEFLCV VSKELHSTPN GLSSESSRKT KSTEEQLEEQ QQQEEEVEEV EVEQVQVEAD AQEKAQSSQD PANLFSLPPL PPPPLPAGGS RPHPLRPEAE LAVRASPRPL ARPQSCHPCC YKPEAPGCEA PDHLQGLGVP I
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation. May be involved in endoplasmic reticulum calcium ion homeostasis.
基因功能參考文獻：
1. A missense mutation in KCTD17 causes autosomal dominant myoclonus-dystonia. PMID: 25983243
相關疾病：

Dystonia 26, myoclonic (DYT26)
亞細胞定位：

Cytoplasm.
組織特異性：

Highly expressed in brain. Highest expression is observed in the putamen and the thalamus.
數據庫鏈接：

HGNC: 25705

OMIM: 616386

KEGG: hsa:79734

UniGene: Hs.517597