Recombinant Human Activating transcription factor 7-interacting protein 2 (ATF7IP2)

中文名稱：

Recombinant Human Activating transcription factor 7-interacting protein 2(ATF7IP2)
貨號：

CSB-YP713182HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Activating transcription factor 7-interacting protein 2(ATF7IP2)
貨號：

CSB-EP713182HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Activating transcription factor 7-interacting protein 2(ATF7IP2)
貨號：

CSB-BP713182HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Activating transcription factor 7-interacting protein 2(ATF7IP2)
貨號：

CSB-MP713182HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ATF7IP2
Uniprot No.：

Q5U623
別名：

ATF7IP2; MCAF2Activating transcription factor 7-interacting protein 2; ATF7-interacting protein 2; MBD1-containing chromatin-associated factor 2
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-682
氨基酸序列

MASPDRSKRK ILKAKKTMPL SCRKQVEMLN KSRNVEALKT AIGSNVPSGN QSFSPSVITR TTEITKCSPS ENGASSLDSN KNSISEKSKV FSQNCIKPVE EIVHSETKLE QVVCSYQKPS RTTESPSRVF TEEAKDSLNT SENDSEHQTN VTRSLFEHEG ACSLKSSCCP PSVLSGVVQM PESTVTSTVG DKKTDQMVFH LETNSNSESH DKRQSDNILC SEDSGFVPVE KTPNLVNSVT SNNCADDILK TDECSRTSIS NCESADSTWQ SSLDTNNNSH YQKKRMFSEN EENVKRMKTS EQINENICVS LERQTAFLEQ VRHLIQQEIY SINYELFDKK LKELNQRIGK TECRNKHEGI ADKLLAKIAK LQRRIKTVLL FQRNCLKPNM LSSNGASKVA NSEAMILDKN LESVNSPIEK SSVNYEPSNP SEKGSKKINL SSDQNKSVSE SNNDDVMLIS VESPNLTTPI TSNPTDTRKI TSGNSSNSPN AEVMAVQKKL DSIIDLTKEG LSNCNTESPV SPLESHSKAA SNSKETTPLA QNAVQVPESF EHLPPLPEPP APLPELVDKT RDTLPPQKPE LKVKRVFRPN GIALTWNITK INPKCAPVES YHLFLCHENS NNKLIWKKIG EIKALPLPMA CTLSQFLASN RYYFTVQSKD IFGRYGPFCD IKSIPGFSEN LT
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable).
基因功能參考文獻：
1. Clinical trial and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20195266
2. These data suggest that MBD1.MCAF1.SETDB1 complex facilitates the formation of heterochromatic domains, emphasizing the role of MCAF/AM family proteins in epigenetic control, and describe a new family member, MCAF2 (ATF7IP2). PMID: 15691849
亞細胞定位：

Nucleus.
蛋白家族：

MCAF family
數據庫鏈接：

HGNC: 20397

OMIM: 613645

KEGG: hsa:80063

STRING: 9606.ENSP00000348799

UniGene: Hs.513343