Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAMTS6), partial

中文名稱：

Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 6(ADAMTS6) ,partial
貨號：

CSB-YP890921HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 6(ADAMTS6) ,partial
貨號：

CSB-EP890921HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 6(ADAMTS6) ,partial
貨號：

CSB-EP890921HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 6(ADAMTS6) ,partial
貨號：

CSB-BP890921HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 6(ADAMTS6) ,partial
貨號：

CSB-MP890921HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ADAMTS6
Uniprot No.：

Q9UKP5
別名：

ADAMTS6; A disintegrin and metalloproteinase with thrombospondin motifs 6; ADAM-TS 6; ADAM-TS6; ADAMTS-6; EC 3.4.24.-
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

基因功能參考文獻：
1. Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. PMID: 30012220
2. High ADAMTS-6 expression is a marker of poor prognosis in patients with esophageal squamous cell carcinoma. PMID: 29475036
3. Using siRNA, over-expression and mutagenesis, it was found ADAMTS6 inhibits and ADAMTS10 is required for focal adhesions, epithelial cell-cell junction formation, and microfibril deposition. PMID: 27779234
4. ADAMTS6 inhibits breast tumor development by regulating the ERK pathway via binding of miR-221-3p PMID: 27542224
5. Novel inguinal hernia susceptibility genes are identified as EFEMP1, WT1, EBF2 and ADAMTS6. PMID: 26686553
6. Study shows that the ADAMTS6 transcript contains unusually large untranslated regions (UTRs) at both the 5' and 3'end, and the 5'UTR contains 11 AUG codons upstream of the predicted ADAMTS6 start codon. PMID: 16129570
7. The gain of function studies indicated that ADAM metallopeptidase with thrombospondin type 1 motif 6 activate NR5A1 gene expression. PMID: 18579725
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亞細胞定位：

Secreted, extracellular space, extracellular matrix.
組織特異性：

Expressed at low levels in placenta and barely detectable in a number of other tissues.
數據庫鏈接：

HGNC: 222

OMIM: 605008

KEGG: hsa:11174

STRING: 9606.ENSP00000370443

UniGene: Hs.482291