Recombinant Escherichia coli Toxin CbtA (cbtA)

中文名稱：

Recombinant Escherichia coli Toxin CbtA(cbtA)
貨號：

CSB-YP354321ENV
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Escherichia coli Toxin CbtA(cbtA)
貨號：

CSB-EP354321ENV
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Escherichia coli Toxin CbtA(cbtA)
貨號：

CSB-EP354321ENV-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Escherichia coli Toxin CbtA(cbtA)
貨號：

CSB-BP354321ENV
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Escherichia coli Toxin CbtA(cbtA)
貨號：

CSB-MP354321ENV
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

cbtA
Uniprot No.：

P64524
別名：

cbtA; yeeV; b2005; JW1987Cytoskeleton-binding toxin CbtA; Toxin CbtA; Toxin YeeV
種屬：

Escherichia coli (strain K12)
蛋白長度：

full length protein
表達區域：

1-124
氨基酸序列

MKTLPVLPGQ AASSRPSPVE IWQILLSRLL DQHYGLTLND TPFADERVIE QHIEAGISLC DAVNFLVEKY ALVRTDQPGF SACTRSQLIN SIDILRARRA TGLMTRDNYR TVNNITLGKY PEAK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Toxic component of a type IV toxin-antitoxin (TA) system. Acts as a dual toxin inhibitor that blocks cell division and cell elongation in genetically separable interactions with FtsZ and MreB. Interacts with cytoskeletal proteins FtsZ and MreB; inhibits FtsZ GTP-dependent polymerization and GTPase activity as well as MreB ATP-dependent polymerization. Binds to both the N- and C-terminus of FtsZ, likely blocking its polymerization and localization, leading to blockage of cell division. Overexpression results in inhibition of growth in liquid cultures and decrease in colony formation; these effects are overcome by concomitant expression of antitoxin CbeA (YeeU). In other experiments cells swell, by 6 hours are lemon-shaped and by 24 hours those that have not lysed are spherical with diminished polar regions. Toxic effects are neutralized by cognate antitoxin CbeA, although there is no direct interaction between the 2 proteins. Toxic effects are also neutralized by overexpression of noncogate antitoxins YafW and YpjF.
亞細胞定位：

Cytoplasm.
蛋白家族：

CbtA/YkfI/YpjF toxin family
數據庫鏈接：

KEGG: ecj:JW1987

STRING: 316385.ECDH10B_2151