Recombinant Drosophila melanogaster Ran-binding proteins 9/10 homolog (RanBPM), partial

中文名稱：

黑腹果蠅RanBPM重組蛋白
貨號：

CSB-YP703398DLU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅RanBPM重組蛋白
貨號：

CSB-EP703398DLU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅RanBPM重組蛋白
貨號：

CSB-EP703398DLU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅RanBPM重組蛋白
貨號：

CSB-BP703398DLU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅RanBPM重組蛋白
貨號：

CSB-MP703398DLU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

RanBPM
Uniprot No.：

Q4Z8K6
別名：

RanBPM; CG42236; Ran-binding proteins 9/10 homolog; Ran-binding protein M
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May be involved in JAK/STAT signaling. Isoform D is required for the proper arrangement of niche cells and is autonomously required for proper niche cell size, isoform C negatively regulates the adhesive properties of the niche. The germline stem cell (GSC) niche in ovaries is made up of two somatic cell types: 8-9 cells in a single-filed array make up the terminal filament (TF), and a tight cluster of 5 or 6 cap cells (CpC). Regulating the size and adhesive properties of the CpCs is an important component of the mechanism that controls their capacity to support stem cells, isoform C and isoform D are important factors in mediating this regulation. In contrast, isoform C acts as a positive regulator of cell adhesion in follicle cell epithelium.
基因功能參考文獻：
1. The role of RanBPM in nervous system function in the context of Drosophila larval behavior, is reported. PMID: 20498842
2. Two RanBPM isoforms are produced from alternatively spliced transcripts, the longer of which is specifically enriched in the germ stem cell (GSC) niche, a cluster of somatic cells that anchors GSCs and expresses signals that maintain GSC fate. PMID: 18762575
亞細胞定位：

Cytoplasm. Membrane. Nucleus. Note=Distribution varies depending on cell type and developmental stage. At late embryogenesis expression is enriched in the nuclei of follicle cells and germline cells and at the nurse cell membranes. In pupal ovaries, expression is seen in niche cells at the cell periphery. In adult ovaries expression is in the nuclei and cytoplasm of the CpCs and TF cells of the niche.
蛋白家族：

RANBP9/10 family
組織特異性：

Expressed in the GSCs and in dividing cysts. Expression is reduced in the germline as individual egg chambers are formed. Isoform C is expressed in all somatic and germline cells of the ovary. Isoform D is expressed in the GSC niche.
數據庫鏈接：

KEGG: dme:Dmel_CG42236

STRING: 7227.FBpp0099887

UniGene: Dm.1508