Recombinant Drosophila melanogaster Protein Smaug (smg), partial

中文名稱：

黑腹果蠅smg重組蛋白
貨號：

CSB-YP630497DLU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅smg重組蛋白
貨號：

CSB-EP630497DLU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅smg重組蛋白
貨號：

CSB-EP630497DLU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅smg重組蛋白
貨號：

CSB-BP630497DLU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅smg重組蛋白
貨號：

CSB-MP630497DLU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

smg
Uniprot No.：

Q23972
別名：

smg; CG5263; Protein Smaug
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Translation regulator that binds to the 3'-UTR of specific mRNAs such as nanos (nos) and prevents their translation. Prevents translation of unlocalized nos in the bulk cytoplasm via the recruitment of cup.
基因功能參考文獻：
1. Smaug regulates the expression of mRNAs encoding glycolytic enzymes (hexokinase and phosophofructokinase), a proteasome regulatory subunit (Rpn7) as well as epigenetic (Su(z)12) and post-transcriptional (Bicaudal C) regulators. PMID: 24393533
2. This paper reports that the Smaug recognition elements in the 3' UTR of nanos (nos) mRNA govern the time- and ATP-dependent assembly of an exceedingly stable repressed ribonucleoprotein particle (RNP) in embryo extract. PMID: 21081899
3. smaug has a domain that encodes a RNA-binding motif PMID: 12372396
4. RNA binds via the SAM domain of smaug. PMID: 12820967
5. the sterile-alpha motif (SAM) domain of Smaug functions as an RNA-recognition domain PMID: 12858164
6. Smaug recruits the CCR4/POP2/NOT deadenylase complex to trigger maternal transcript localization in the early Drosophila embryo. PMID: 15723788
7. Smaug accumulation thus coordinates progression through the maternal-to-zygotic transition PMID: 19234062
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亞細胞定位：

Cytoplasm. Note=In the cytoplasm of syncytial embryos, accumulates in discrete foci.
蛋白家族：

SMAUG family
組織特異性：

At syncytial blastoderm, it is located throughout the bulk cytoplasm and pole plasm. By the time of cellularization, it concentrates at the posterior pole.
數據庫鏈接：

KEGG: dme:Dmel_CG5263

STRING: 7227.FBpp0288542

UniGene: Dm.2553