Recombinant Drosophila melanogaster Integrin beta-PS (mys), partial
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中文名稱：黑腹果蠅mys重組蛋白
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貨號：CSB-EP319315DLU-B
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說明書：
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規(guī)格：
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來源：E.coli
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共軛：Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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其他：
產(chǎn)品詳情
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純度：>85% (SDS-PAGE)
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基因名：mys
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Uniprot No.：
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別名：mys; l(1)mys; olfC; CG1560; Integrin beta-PS; Position-specific antigen beta subunit; Protein myospheroid; Protein olfactory C
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種屬：Drosophila melanogaster (Fruit fly)
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蛋白長度：Partial
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蛋白標簽：Tag?type?will?be?determined?during?the?manufacturing?process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. -
產(chǎn)品提供形式：Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
復溶：We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
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儲存條件：Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質(zhì)期：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事項：Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet ：Please contact us to get it.
產(chǎn)品評價
靶點詳情
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功能：Integrin alpha-PS1/beta-PS is a receptor for laminin. Integrin alpha-PS2/beta-PS is a receptor for Tig, wb and Ten-m. Contributes to endodermal integrity and adhesion between the midgut epithelium and the surrounding visceral muscle. Essential for migration of the primordial midgut cells and for maintaining, but not establishing, cell polarity in the midgut epithelium. The two beta subunits mediate midgut migration by distinct mechanisms: beta-PS requires rhea/talin and Itgbn does not. Required for rhea/talin correct cellular localization in the midgut. Required for many embryonic (dorsal closure and somatic muscle attachments) and postembryonic developmental processes (attachment between cell layers of imaginal disks, organization of ommatidial arrays and flight muscle development). Involved in the function and/or development of the olfactory system. In the testes, essential for shv-dependent maintenance of somatic hub cells and their localization to the apical tip. Plays a role in timely border cell migration during oogenesis.
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基因功能參考文獻：
- analysis of integrin beta subunit mutations that alter affinity for extracellular matrix ligand PMID: 21757698
- Dei's expression is restricted to intervein territories where it acts as a potent activator of betaPS integrin expression PMID: 21215259
- Study finds that the integrin subunit Mys is required only for monolayer formation; these results indicate that collapse, spreading and monolayer formation are not only temporally distinct, but also probably molecularly distinct. PMID: 20530544
- mutation of betaPS integrin subunit has dominant negative properties in developing Drosophila PMID: 11950944
- Delayed behavioral aging is influenced by the beta-integrin protein (betaPS). PMID: 14570233
- The C8-C9 loop of the betaPS subunit contains structural information that can differentially regulate integrin activity. PMID: 14980507
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亞細胞定位：Apical cell membrane; Single-pass type I membrane protein. Lateral cell membrane; Single-pass type I membrane protein. Basal cell membrane; Single-pass type I membrane protein. Note=In ovary, localizes to the apical, lateral and basal membranes of follicle cells through oogenesis stage 10A. Apical membrane expression peaks at oogenesis stages 9 and 10A in columnar follicle cells overlying the oocyte but decreases in the most posterior follicle cells. Thereafter, it is down-regulated. Localization to lateral and basal membranes persists during dorsal appendage morphogenesis.
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蛋白家族：Integrin beta chain family
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組織特異性：In ovaries, strongly expressed in follicle cells. In oocytes, expressed in the forming dorsal appendages (at protein level). Expressed in the embryonic dorsal cuticle, the larval eye and the wing imaginal disk. In testes, detected at the interface between
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