Recombinant Drosophila melanogaster Heat shock factor protein (Hsf), partial

中文名稱：

黑腹果蠅Hsf重組蛋白
貨號：

CSB-YP338468DLU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅Hsf重組蛋白
貨號：

CSB-EP338468DLU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅Hsf重組蛋白
貨號：

CSB-EP338468DLU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅Hsf重組蛋白
貨號：

CSB-BP338468DLU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅Hsf重組蛋白
貨號：

CSB-MP338468DLU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Hsf
Uniprot No.：

P22813
別名：

Hsf; CG5748; Heat shock factor protein; HSF; Heat shock transcription factor; HSTF
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.
基因功能參考文獻：
1. Azadiradione ameliorates polyglutamine expansion disease in Drosophila by potentiating DNA binding activity of heat shock factor 1. PMID: 27835876
2. HSF role in the heat shock response to viral infection PMID: 26234525
3. HSF is dispensable for establishing or maintaining Pol II pausing but is critical for the release of paused Pol II into the gene body at a subset of highly activated genes PMID: 27492368
4. The survival curves of heterozygotes on hsf-1 and hsf-4 alleles are similar in spite of HSF-4 protein is slightly active on normal temperature. PMID: 26856085
5. Physiological function of mutated HSF4 is not fully abrogated after heat exposure and is able to recover even after severe heat stress, causing the induction of heat-shock gene expression. PMID: 25850300
6. HSF may be regulating many genes besides the known HS genes and that some of these genes may be regulated during non-stress conditions PMID: 21264254
7. HSF binds to nmnat promoter and induces NMNAT expression under heat shock. In contrast, under hypoxia, HIF1alpha up-regulates NMNAT indirectly through the induction of HSF PMID: 21478149
8. Recruitment of the master regulator, HSF, is first detected within 20 s of gene activation. PMID: 21172661
9. The genome-wide distribution of Drosophila Heat Shock Factor (HSF), a transcription factor whose binding activity is mediated by heat shock-induced trimerization, was examined. PMID: 20844575
10. Three new alternatively spliced isoforms of Drosophila HSF (dHSF) mRNA, named dHSFb, dHSFc, and dHSFd were identified. PMID: 15978579
11. heat shock factor transcription is up-regulated during hypoxia due to direct binding by hypoxia-inducible factor-1 PMID: 17040902
12. Life span alteration after irradiation in Drosophila melanogaster strains with mutations of Hsf and Hsps. PMID: 18551381
13. HSF regulates the expression of several uncharacterized genes induced by a short non-lethal heat treatment:cg-13227,-13664,-32130. cg-6332 & 18331 did not seem to require HSF> PMID: 18759003
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亞細胞定位：

Nucleus.
蛋白家族：

HSF family
數據庫鏈接：

KEGG: dme:Dmel_CG5748

UniGene: Dm.4107