Recombinant Drosophila melanogaster Deoxyhypusine hydroxylase (nero)

中文名稱：

黑腹果蠅nero重組蛋白
貨號：

CSB-YP892698DLU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅nero重組蛋白
貨號：

CSB-EP892698DLU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅nero重組蛋白
貨號：

CSB-EP892698DLU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅nero重組蛋白
貨號：

CSB-BP892698DLU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅nero重組蛋白
貨號：

CSB-MP892698DLU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

nero
Uniprot No.：

Q9V9U4
別名：

nero; l(3)s1921; CG2245Deoxyhypusine hydroxylase; DOHH; EC 1.14.99.29; Deoxyhypusine dioxygenase; Deoxyhypusine monooxygenase
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

full length protein
表達區域：

1-302
氨基酸序列

MVSQQQIEAI GGVLNNKERP LKERFRALFT LKNIGGGAAI EAISKAFDDD SALLKHELAY CLGQMQDAQA LDILTKVLKD TTQEPMVRHE AAEAMGAIGH PDVLPILEEY KQDPVVEVAE TCAIALDRVR WLQSGQKVDD SNPYASVDPS PPTAGDKSVT ELKAIYLDAQ QSLFDRYRAM FSLRNLRTEE SVLAIAEGLK DSSALFRHEV AFVLGQLQEP CSIPFLQENL EDRLENEMVR HECAEALGAI ATEDCIQILN RYAEDDKRVV KESCVIALDM CEYENSPEFQ YADGLAKLDA TK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. Essential for organismal viability and plays a role in a wide number of important processes such as cell growth and proliferation, and regulates induction of autophagy and protein synthesis. Has a role in eIF-5A-mediated translational control.
基因功能參考文獻：
1. Results describe the identification and characterization of nero (CG2245), the Drosophila melanogaster deoxyhypusine hydroxylase (DOHH) homologue, and indicate that nero and eIF5A are required for cell growth and affect autophagy and protein synthesis. PMID: 19546244
亞細胞定位：

Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=In larval imaginal disk and Garland cells.
蛋白家族：

Deoxyhypusine hydroxylase family
數據庫鏈接：

KEGG: dme:Dmel_CG2245

STRING: 7227.FBpp0085222

UniGene: Dm.29814