Recombinant Dog NADH-cytochrome b5 reductase 3 (CYB5R3)

中文名稱：

Recombinant Dog NADH-cytochrome b5 reductase 3(CYB5R3)
貨號：

CSB-YP607302DO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Dog NADH-cytochrome b5 reductase 3(CYB5R3)
貨號：

CSB-EP607302DO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Dog NADH-cytochrome b5 reductase 3(CYB5R3)
貨號：

CSB-EP607302DO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Dog NADH-cytochrome b5 reductase 3(CYB5R3)
貨號：

CSB-BP607302DO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Dog NADH-cytochrome b5 reductase 3(CYB5R3)
貨號：

CSB-MP607302DO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

CYB5R3
Uniprot No.：

Q0X0E5
別名：

CYB5R3; C5BR; DIA1; NADH-cytochrome b5 reductase 3; B5R; Cytochrome b5 reductase; EC 1.6.2.2; Diaphorase-1) [Cleaved into: NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form]
種屬：

Canis familiaris (Dog) (Canis lupus familiaris)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-301
氨基酸序列

GAQLSTLGH VVLSPVWFLY NLLMKLFQRS TPAITLESPD IKYPLRLIDK EVINHDTRRF RFALPSPQHI LGLPVGQHIY LSARIDGNLV IRPYTPVSSD DDKGFVDLVI KVYFKDTHPK FPAGGKMSQY LESMKIGDTI EFRGPNGLLV YQGKGKFAIR PDKKSNPIIK TVKSVGMIAG GTGITPMLQV IRAIIKDPHD PTVCHLLFAN QTEKDILLRP ELEELRNEHS ARFKLWYTVD KAPEAWDYSQ GFVNEEMIRD HLPPPEEEPL ILMCGPPPMI QYACLPNLDR VGHPKERCFA F
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.
基因功能參考文獻：
1. All Doberman Pinschers in this study were homozygous for CYB5R3 729G, which could contribute to this breed's apparent predisposition to sulfonamide hypersensitivity; the study also showed that CYB5R3 729G does not alter sulfamethoxazole detoxification capacity. PMID: 29336038
2. Familial congenital methemoglobinemia seen in a Pomeranian dog family was caused by congenital NADH-cytochrome b5 reductase deficiency due to a missense variant, c.580A>C, in the CYB5R3 gene. PMID: 29356095
亞細胞定位：

Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Mitochondrion outer membrane; Lipid-anchor; Cytoplasmic side.
蛋白家族：

Flavoprotein pyridine nucleotide cytochrome reductase family
數據庫鏈接：

KEGG: cfa:474479

STRING: 9615.ENSCAFP00000001359

UniGene: Cfa.15074