Recombinant Dictyostelium discoideum Sodium/hydrogen exchanger 1 (nhe1), partial

中文名稱(chēng)：

盤(pán)基網(wǎng)柄菌nhe1重組蛋白
貨號(hào)：

CSB-YP709912DKK
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

盤(pán)基網(wǎng)柄菌nhe1重組蛋白
貨號(hào)：

CSB-EP709912DKK
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

盤(pán)基網(wǎng)柄菌nhe1重組蛋白
貨號(hào)：

CSB-EP709912DKK-B
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

盤(pán)基網(wǎng)柄菌nhe1重組蛋白
貨號(hào)：

CSB-BP709912DKK
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

盤(pán)基網(wǎng)柄菌nhe1重組蛋白
貨號(hào)：

CSB-MP709912DKK
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

nhe1
Uniprot No.：

Q552S0
別名：

nhe1; DDB_G0275711; Sodium/hydrogen exchanger 1; DdNHE1; NHE1; Na-H exchanger 1
種屬：

Dictyostelium discoideum (Slime mold)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Regulation of intracellular pH homeostasis in response to cAMP, which is essential for chemotaxis. Necessary for F-actin localization and the kinetics of actin polymerization during chemotaxis and cell polarity but not for directional sensing.
基因功能參考文獻(xiàn)：
1. Htt and Nhel play roles in the same specific cation-facilitated behaviors and Nhel localization is directly or indirectly regulated by Htt. PMID: 25149514
2. Nhe1 is essential for potassium facilitation of cell motility and the monovalent cation requirement for chemotactic orientation. PMID: 21239624
3. Data indicate a cooperative role of Aip1 and cofilin in pH-dependent cell migration, and they suggest defective chemotaxis in Ddnhe1(-) cells is determined primarily by loss of cofilin-dependent actin dynamics. PMID: 20668166
亞細(xì)胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family
數(shù)據(jù)庫(kù)鏈接：

KEGG: ddi:DDB_G0275711

STRING: 44689.DDB0231789