Recombinant Dictyostelium discoideum Ras-related protein rapA (rapA)

中文名稱：

盤基網柄菌rapA重組蛋白
貨號：

CSB-YP323862DKK
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

盤基網柄菌rapA重組蛋白
貨號：

CSB-EP323862DKK
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

盤基網柄菌rapA重組蛋白
貨號：

CSB-EP323862DKK-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

盤基網柄菌rapA重組蛋白
貨號：

CSB-BP323862DKK
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

盤基網柄菌rapA重組蛋白
貨號：

CSB-MP323862DKK
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

rapA
Uniprot No.：

P18613
別名：

rapA; rap1; DDB_G0291237; Ras-related protein rapA; Ras-related protein rap-1
種屬：

Dictyostelium discoideum (Slime mold)
蛋白長度：

full length protein
表達區域：

1-183
氨基酸序列

MPLREFKIVV LGSGGVGKSA LTVQFVQGIF VEKYDPTIED SYRKQVEVDS NQCMLEILDT AGTEQFTAMR DLYMKNGQGF VLVYSIISNS TFNELPDLRE QILRVKDCED VPMVLVGNKC DLHDQRVIST EQGEELARKF GDCYFLEASA KNKVNVEQIF YNLIRQINRK NPVGPPSKAK SKC
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

G protein of the Ras family that positively regulates phagocytosis and negatively regulates macropinocytosis. May be involved in the activation of guanylyl cyclase during the response to hyperosmotic conditions. Overexpressing cells generate alterations in cell shape and contractile responses. Involved in chemotaxis via regulation of the balance of Ras and Rap signaling at the leading edge of chemotaxing cells.
基因功能參考文獻：
1. Results from comparative proteomics identified Rap1 as a novel legionella-containing-vacuole host component implicated in intracellular replication of Legionella pneumophila. PMID: 28183814
2. TalinB and Rap1 is necessary for adhesion of Dictyostelium cells. PMID: 26744136
3. Rap1 drives cytokinesis progression by coordinating the three major cytoskeletal components: microtubules, actin, and myosin II. PMID: 25298405
亞細胞定位：

Cell membrane; Lipid-anchor; Cytoplasmic side.
蛋白家族：

Small GTPase superfamily, Ras family
數據庫鏈接：

KEGG: ddi:DDB_G0291237

STRING: 44689.DDB0216229