Recombinant Dictyostelium discoideum Des-methyl DIF-1 methyltransferase A (dmtA)

中文名稱：

盤基網柄菌dmtA重組蛋白
貨號：

CSB-YP837407DKK
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

盤基網柄菌dmtA重組蛋白
貨號：

CSB-EP837407DKK
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

盤基網柄菌dmtA重組蛋白
貨號：

CSB-EP837407DKK-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

盤基網柄菌dmtA重組蛋白
貨號：

CSB-BP837407DKK
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

盤基網柄菌dmtA重組蛋白
貨號：

CSB-MP837407DKK
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

dmtA
Uniprot No.：

Q8T638
別名：

dmtA; omt8; DDB_G0289329Des-methyl DIF-1 methyltransferase A; EC 2.1.1.-; O-methyltransferase 8
種屬：

Dictyostelium discoideum (Slime mold)
蛋白長度：

full length protein
表達區域：

1-363
氨基酸序列

MISNSDCDEN LIKQQQQEIQ DKNFLIDVAI GYTKSNALSC ALKYKIPQLL EDKSKSCKEL SEILKVNCDN LYRLLRTLST IGIFIEDEVE DGVFRNSRLS NLLRNSNSDS WVNNVYLQSH PNVIQSFMYL DKTIECGTSQ GMTSQGFSSA WELFEKDKSL NAHFHNTMTS FTSDEIKTIL EYIDFNQYKS IVDLGGSSGE LLKSIAKSSR GQLVESFINF DLPLVINQNK VNNENGAAEF DKRYSEVASD LFVDSDYPSA DCYTLKFIFH MFNDDKVLTI LDKISKSIKP NGKVYVFDHI VQPKNQPYAP FYFDLQMIVN FNGKERSQNE WKTIFEKSPF KIDTILILPD SKRMSVIELS LKQ
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

O-methyltransferase; part of the gene cluster that mediates the biosynthesis of DIF-1 (Differentiation Inducing Factor-1), a signal molecule involved in the differentiation of pstO (prestalk-O) cells. The three-step process begins with the formation of (2,4,6-trihydroxyphenyl)-1-hexan-1-one (THPH) by the polyketide synthase StlB. THPH is then dichlorinated by the flavin-dependent halogenase ChlA. The last step of DIF-1 biosynthesis is the O-methylation of dichloro-THPH (or des-methyl-DIF-1) by the methyltransferase DmtA to yield DIF-1.
基因功能參考文獻：
1. Differentiation-inducing factor-1 promotes glucose uptake via inhibitors for phosphatidylinositol 3-kinase/Akt-independent pathway in mammalian cells. PMID: 17553062
蛋白家族：

Class I-like SAM-binding methyltransferase superfamily, Cation-independent O-methyltransferase family, COMT subfamily
數據庫鏈接：

KEGG: ddi:DDB_G0289329

STRING: 44689.DDB0219945