Recombinant Danio rerio Smith-Magenis syndrome chromosomal region candidate gene 8-B protein homolog (smcr8b), partial

中文名稱：

斑馬魚smcr8b重組蛋白
貨號：

CSB-YP744146DIL
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

斑馬魚smcr8b重組蛋白
貨號：

CSB-EP744146DIL
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

斑馬魚smcr8b重組蛋白
貨號：

CSB-EP744146DIL-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

斑馬魚smcr8b重組蛋白
貨號：

CSB-BP744146DIL
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

斑馬魚smcr8b重組蛋白
貨號：

CSB-MP744146DIL
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

smcr8b
Uniprot No.：

Q6PUR7
別名：

smcr8b; smcr8; Guanine nucleotide exchange protein smcr8b; Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog B
種屬：

Danio rerio (Zebrafish) (Brachydanio rerio)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 668
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity.
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

SMCR8 family
數據庫鏈接：

KEGG: dre:407723

STRING: 7955.ENSDARP00000005452

UniGene: Dr.113437