Recombinant Corynebacterium glutamicum GDP-mannose-dependent alpha- (1-6)-phosphatidylinositol monomannoside mannosyltransferase (pimB)

中文名稱：

谷氨酸棒狀桿菌pimB重組蛋白
貨號：

CSB-YP847774DWY
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

谷氨酸棒狀桿菌pimB重組蛋白
貨號：

CSB-EP847774DWY
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

谷氨酸棒狀桿菌pimB重組蛋白
貨號：

CSB-EP847774DWY-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

谷氨酸棒狀桿菌pimB重組蛋白
貨號：

CSB-BP847774DWY
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

谷氨酸棒狀桿菌pimB重組蛋白
貨號：

CSB-MP847774DWY
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

pimB
Uniprot No.：

Q8NNK8
別名：

pimB; Cgl2186; cg2400; GDP-mannose-dependent monoacylated alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase; EC 2.4.1.346; Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Alpha-mannosyltransferase; Alpha-ManT; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase
種屬：

Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
蛋白長度：

full length protein
表達區域：

1-381
氨基酸序列

MSASRKTLVV TNDFPPRIGG IQSYLRDFIA TQDPESIVVF ASTQNAEEAH AYDKTLDYEV IRWPRSVMLP TPTTAHAMAE IIREREIDNV WFGAAAPLAL MAGTAKQAGA SKVIASTHGH EVGWSMLPGS RQSLRKIGTE VDVLTYISQY TLRRFKSAFG SHPTFEHLPS GVDVKRFTPA TPEDKSATRK KLGFTDTTPV IACNSRLVPR KGQDSLIKAM PQVIAARPDA QLLIVGSGRY ESTLRRLATD VSQNVKFLGR LEYQDMINTL AAADIFAMPA RTRGGGLDVE GLGIVYLEAQ ACGVPVIAGT SGGAPETVTP ATGLVVEGSD VDKLSELLIE LLDDPIRRAA MGAAGRAHVE AEWSWEIMGE RLTNILQSEP R
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM). Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose residues (Ac1PIM2). PimB also catalyzes the addition of a mannosyl residue from GDP-Man to the position 6 of phosphatidyl-myo-inositol bearing an acylated alpha-1,2-linked mannose residue (Ac1PIM1) to generate monoacylated phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose residues (Ac1PIM2). The addition of the second mannosyl residue by PimB preferentially occurs before the acylation of the mannosyl residue transferred by PimA. Also able to transfer a mannosyl residue from GDP-Man to the position 6 of a phosphatidyl-myo-inositol (PI), but this reaction is very slow.
基因功能參考文獻：
1. PimB' (NCgl2106) attaches mannosyl selectively to the 6-OH of the inositol moiety of phosphatidyl-myo-inositol. PMID: 20843801
蛋白家族：

Glycosyltransferase group 1 family, Glycosyltransferase 4 subfamily
數據庫鏈接：

KEGG: cgb:cg2400

STRING: 196627.cg2400