Recombinant Chicken Low-density lipoprotein receptor-related protein 8 (LRP8), partial

中文名稱：

雞LRP8重組蛋白
貨號：

CSB-YP842998CH
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

雞LRP8重組蛋白
貨號：

CSB-EP842998CH
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

雞LRP8重組蛋白
貨號：

CSB-EP842998CH-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

雞LRP8重組蛋白
貨號：

CSB-BP842998CH
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

雞LRP8重組蛋白
貨號：

CSB-MP842998CH
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

LRP8
Uniprot No.：

Q98931
別名：

LRP8; LR8B; Low-density lipoprotein receptor-related protein 8; LRP-8; Apolipoprotein E receptor 2; Protein LR8B
種屬：

Gallus gallus (Chicken)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. Also binds alpha2-macroglobulin. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. Not required for endocytic uptake of SEPP1 in the kidney which is mediated by LRP2.
基因功能參考文獻：
1. ApoER2 transcripts are expressed in the digit cartilages. Reelin promotes chondrogenesis through ApoER2. PMID: 24519818
2. Genotype of LRP8 is associated with egg-type layres from several chicken families. PMID: 20371838
亞細胞定位：

Membrane; Single-pass type I membrane protein.
蛋白家族：

LDLR family
組織特異性：

Mainly in brain.
數據庫鏈接：

KEGG: gga:396102

STRING: 9031.ENSGALP00000017370

UniGene: Gga.3461