Recombinant Bovine UPF0609 protein C4orf27 homolog

中文名稱：

牛HPF1重組蛋白
貨號：

CSB-YP384849BO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

牛HPF1重組蛋白
貨號：

CSB-EP384849BO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

牛HPF1重組蛋白
貨號：

CSB-EP384849BO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

牛HPF1重組蛋白
貨號：

CSB-BP384849BO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

牛HPF1重組蛋白
貨號：

CSB-MP384849BO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

HPF1
Uniprot No.：

A2VDY4
別名：

HPF1Histone PARylation factor 1
種屬：

Bos taurus (Bovine)
蛋白長度：

full length protein
表達區域：

1-346
氨基酸序列

MVGGGAKRRL RGEGPQCEKP VDMKKSKSCE ADVPGDLRKE VESHYRLPLP EDFYHFWRFC EGLDPEQPAD SLSASLGLRL VGPYDILAGK HKIKKKSASL NFNLHWRFYY DPPEFQTIII GDSKTQFHMG YFRDSPDELP VFVGTNEAKK NCIIVQSGDN VFAAVKLFLM KKLKEVTDKK KSSLLKTIDE KLTEAARELG FSLEQRTVRM KQRDKKVVTK TFHGAGLVVP VDKNDVGYRE LPETDASLRR ICGTIVEAPS DADRLQAFAP VQEMMTYVQF ANDECDYGMG LELGLDLFCH GSHYFHKVAG QLLPLAYNLL KRNLFAEIIE AHLANRSQDD VDQLAA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Cofactor for serine ADP-ribosylation that confers serine specificity on PARP1 and PARP2 and plays a key role in DNA damage response. Initiates the repair of double-strand DNA breaks: recruited to DNA damage sites by PARP1 and PARP2 and switches the amino acid specificity of PARP1 and PARP2 from aspartate or glutamate to serine residues, licensing serine ADP-ribosylation of target proteins. Serine ADP-ribosylation of target proteins, such as histones, promotes decompaction of chromatin and the recruitment of repair factors leading to the reparation of DNA strand breaks. Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage. HPF1 acts by completing the active site of PARP1 and PARP2: forms a composite active site composed of residues from HPF1 and PARP1 or PARP2. HPF1 also promotes tyrosine ADP-ribosylation, probably by conferring tyrosine specificity on PARP1.
亞細胞定位：

Chromosome. Nucleus.
蛋白家族：

HPF1 family
數據庫鏈接：

KEGG: bta:525698

STRING: 9913.ENSBTAP00000026815

UniGene: Bt.44222