Recombinant Bovine Protein HEXIM1 (HEXIM1)
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中文名稱：牛HEXIM1重組蛋白
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貨號：CSB-EP605893BO-B
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說明書：
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規格：
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來源：E.coli
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共軛：Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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其他：
產品詳情
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純度：>85% (SDS-PAGE)
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基因名：HEXIM1
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Uniprot No.：
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別名：HEXIM1; Protein HEXIM1
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種屬：Bos taurus (Bovine)
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蛋白長度：full length protein
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表達區域：1-320
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氨基酸序列MAEPLLSEFQ HQPQTSNCTG AVAVHEERNP DRPPGAEERV PEEDSRWQSR ASPKSGGSPG HGGEGSLEPQ PSPLKTQVCP ESSCPEAGEK GQNGDDLSAG GAPPQQRQVG KKKHRRRPSK KKRLWKPYYT LTWEEKKKFD EKQSLRASRI RAEMFAKGQP VAPYNTTQFL MDDHDQEEPD LKTGLYPKRA AAKSDDTSDE DFMEEAGEED GGSDGMGGDG SEFLQRDFSE TYERYHAESL QNMSKQELIK EYLELEKCLS RMEDENNRLR LESQRLDGDD ARVRELELEL DRLRAENLQL LTENELHRQQ ERAPLSNFGD
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蛋白標簽：Tag?type?will?be?determined?during?the?manufacturing?process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. -
產品提供形式：Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
復溶：We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
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儲存條件：Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質期：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事項：Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet ：Please contact us to get it.
產品評價
靶點詳情
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功能：Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.
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基因功能參考文獻：
- The authors demonstrate that bovine hexamethylene bisacetamide-induced protein 1 (BHEXIM1) inhibits the bovine immunodeficiency virus-mediated BIV LTR transcription. In vivo and in vitro assays show direct binding of BHEXIM1 to the bovine cyclin T1. PMID: 23537346
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亞細胞定位：Nucleus. Cytoplasm.
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蛋白家族：HEXIM family
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數據庫鏈接：
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