Recombinant Bovine Nitric oxide synthase-interacting protein (NOSIP)

中文名稱：

牛NOSIP重組蛋白
貨號：

CSB-YP662240BO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

牛NOSIP重組蛋白
貨號：

CSB-EP662240BO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

牛NOSIP重組蛋白
貨號：

CSB-EP662240BO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

牛NOSIP重組蛋白
貨號：

CSB-BP662240BO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

牛NOSIP重組蛋白
貨號：

CSB-MP662240BO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

NOSIP
Uniprot No.：

Q3SWY5
別名：

NOSIPNitric oxide synthase-interacting protein; E3 ubiquitin-protein ligase NOSIP; EC 2.3.2.27; RING-type E3 ubiquitin transferase NOSIP
種屬：

Bos taurus (Bovine)
蛋白長度：

full length protein
表達區域：

1-302
氨基酸序列

MTRHGKNCTA GAVYTYHEKK KDTAASGYGT QNIRLSRDAV KDFDCCCLSL QPCHDPVVTP DGYLYEREAI LEYILHQKKE IARQMKAYEK QRGARREEQK ELQRAAAQDH VRGFLEKEAA IVSRPLNPFT PKAASAGNGP DDAQPGSSAG PAGKDKDKAL PSFWIPSLTP EAKATKLEKP SRIVTCPMSG KPLRMSDLTP VRFTPLDSSV DRVGLITRSE RYVCAVTRDS LSNATPCAVL RPSGAVVTLE CVEKLIRKDM VDPVTGEKLT DRDIIVLQRG GTGFAGSGVK LQAEKSRPVM QA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB. Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
基因功能參考文獻：
1. Hydrogen peroxide down regulates endothelial dihydrofolate reductase expression in response to angiotensin Ii and underlies endothelial nitric oxide synthase dysfunction. PMID: 15941833
2. Cdc37 has a direct regulatory interaction with endothelial nitric oxide synthase (eNOS) and may play an important role in mediating the eNOS protein complex formation. PMID: 16410463
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

NOSIP family
數據庫鏈接：

KEGG: bta:511234

STRING: 9913.ENSBTAP00000019215

UniGene: Bt.10405