Recombinant Bovine A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4), partial

中文名稱：

Recombinant Bovine A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAMTS4) ,partial
貨號(hào)：

CSB-YP874673BO
說(shuō)明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

Recombinant Bovine A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAMTS4) ,partial
貨號(hào)：

CSB-EP874673BO
說(shuō)明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

Recombinant Bovine A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAMTS4) ,partial
貨號(hào)：

CSB-EP874673BO-B
說(shuō)明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Bovine A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAMTS4) ,partial
貨號(hào)：

CSB-BP874673BO
說(shuō)明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

Recombinant Bovine A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAMTS4) ,partial
貨號(hào)：

CSB-MP874673BO
說(shuō)明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

ADAMTS4
Uniprot No.：

Q9TT93
別名：

ADAMTS4A disintegrin and metalloproteinase with thrombospondin motifs 4; ADAM-TS 4; ADAM-TS4; ADAMTS-4; EC 3.4.24.82; ADMP-1; Aggrecanase-1
種屬：

Bos taurus (Bovine)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
基因功能參考文獻(xiàn)：
1. ADAMTS4 participates in the regulation of muscle development in cattle. PMID: 24222240
2. aggrecanase activity (a) is responsible for early TNFalpha-dependent aggrecan cleavage and GAG release in the meniscus and (b) might be involved in meniscal degeneration. PMID: 19778432
3. ADAMTS4 and ADAMTS5 are inhibited by alpha2-macroglobulin PMID: 14715656
4. identified multiple conserved amino acids within regions N- and C-terminal to the site of scission that may influence enzyme-substrate recognition, and may interact with exosites on ADAMTS-4 and ADAMTS-5 PMID: 19101611
亞細(xì)胞定位：

Secreted, extracellular space, extracellular matrix.
數(shù)據(jù)庫(kù)鏈接：

KEGG: bta:286806

STRING: 9913.ENSBTAP00000017583

UniGene: Bt.15675