SN38 Recombinant Monoclonal Antibody
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中文名稱：SN38重組抗體
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貨號：CSB-RA187707I1m
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規格：￥3000
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圖片：
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The Binding Activity of Labetuzumab govitecan (Synonyms: IMMU 130; hMN-14-SN-38) with Anti-SN38 antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Labetuzumab govitecan (Synonyms: IMMU 130; hMN-14-SN-38) at 2 μg/mL can bind Anti-SN38 antibody, the EC50 is 3.326 to 4.721 ng/mL.
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其他：
產品詳情
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產品描述：SN38 Recombinant Monoclonal Antibody（Code: CSB-RA187707I1m）是一種高特異性抗體，靶向SN38分子（7-ethyl-10-hydroxycamptothecin），該分子是拓撲異構酶I抑制劑伊立替康的活性代謝產物，在腫瘤研究領域被廣泛用于誘導DNA損傷及細胞凋亡機制研究。本抗體通過重組技術制備，經ELISA方法嚴格驗證，在1:5000至1:50000的寬泛稀釋范圍內表現出優異的檢測靈敏度和線性關系，可精準識別天然構象的SN38分子。其高批次穩定性與低交叉反應性設計，適用于定量分析SN38在細胞模型或體外藥理學研究中的分布與作用，例如評估藥物遞送效率、代謝動力學或腫瘤細胞耐藥性機制等實驗場景。推薦應用于ELISA平臺檢測，支持細胞培養上清、裂解液等樣本類型的分析，為抗腫瘤藥物開發及分子毒理學研究提供可靠工具。該產品僅供科研使用，不涉及任何臨床相關用途。
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基因名：SN38
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別名：SN38, 7-Ethyl-10-hydroxycamptothecin
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反應種屬：Human
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免疫原：SN38-BSA
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標記方式：Non-conjugated
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克隆類型：Monoclonal
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抗體亞型：IgG2a
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純化方式：Affinity-chromatography
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克隆號：10G11D5
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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推薦稀釋比：
Application Recommended Dilution ELISA 1:5000-1:50000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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