IL12&IL23 monoclonal antibody
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中文名稱：IL12&IL23重組抗體
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貨號：CSB-RA011587MA1HU
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規格：￥1320
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圖片：
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The Binding Activity of IL12B&IL12A with Anti-IL12/IL23 monoclonal antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL12B&IL12A (CSB-MP4155HU) at 1 μg/mL can bind Anti-IL12/IL23 recombinant antibody, the EC50 is 1.042-1.545 ng/mL. -
IHC image of CSB-RA011587MA1HU diluted at 1:50 and staining in paraffin-embedded human lymphnode tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.
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產品詳情
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產品描述：CSB-RA011587MA1HU IL12&IL23重組單克隆抗體是針對IL-12和IL-23雙靶點設計的高特異性科研工具，適用于ELISA檢測。該抗體靶向IL-12（由p35和p40亞基組成）和IL-23（由p19和p40亞基組成），這兩種細胞因子通過共享的p40亞基參與免疫調控，能夠分別激活Th1和Th17細胞通路，在自身免疫性疾病及炎癥反應中發揮關鍵作用。經ELISA驗證，本品可同時識別天然構象下的IL-12和IL-23蛋白，具有高親和力與低交叉反應性，其重組單克隆特性保障了實驗數據的可重復性。科研人員可將其用于體外模型中的細胞因子定量分析、免疫應答機制研究，以及相關藥物靶點篩選等基礎研究領域，為探索銀屑病、炎癥性腸病等疾病的病理機制提供可靠工具。本產品嚴格限于科學研究使用，不涉及任何臨床或診斷用途。
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Uniprot No.：
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基因名：IL12&IL23
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別名：IL12&IL23 monoclonal antibody
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反應種屬：Human
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免疫原：Recombinant Human IL12&IL23 protein
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Monoclonal
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抗體亞型：hIgG1
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純化方式：Affinity-chromatography
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克隆號：14D4
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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