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中文名稱：Claudin-18.2重組抗體
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貨號：CSB-RA005498A1HU
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規格：￥1320
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圖片：
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Untransfected KATO3 cells surface (green line), transfected Human CLDN18.2 KATO3 stable cells surface (red line) and transfected Human CLDN18.1 NIH-3T3 stable cells surface (blue line) were stained with anti-CLDN18.2 antibody (2μg/1*106 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. -
The Binding Activity of Human CLDN18.2 with Anti-CLDN18.2 recombinant antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLDN18.2 (CSB-MP005498HU(A5)) at 5 μg/mL can bind Anti-CLDN18.2 recombinant antibody, the EC50 is 6.554-27.87 ng/mL.
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其他：
產品詳情
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產品描述：CSB-RA005498A1HU Claudin-18.2重組單克隆抗體是針對緊密連接蛋白家族成員Claudin-18.2研發的高特異性科研試劑。該靶點通過調控上皮細胞間緊密連接參與屏障功能維持，其亞型Claudin-18.2在胃癌、胰腺癌等消化道腫瘤中呈現特異性高表達，成為腫瘤生物學研究的重要生物標志物。本抗體經ELISA和流式細胞術（FC）雙重驗證，在FC應用中推薦使用1:50-1:200的稀釋范圍，可精準識別天然構象的膜表面抗原，適用于活細胞或固定化樣本的定量檢測。該產品憑借優異的批間一致性和低交叉反應特性，可支持腫瘤細胞表面標記物分析、靶向藥物體外篩選模型構建以及腫瘤微環境中細胞亞群分選等研究場景，為探索Claudin-18.2在腫瘤發生、轉移及耐藥機制中的功能提供可靠工具，助力抗腫瘤藥物開發及轉化醫學研究。本產品嚴格限定于體外實驗及基礎科研用途。
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Uniprot No.：
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基因名：
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別名：Claudin-18, CLDN18
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反應種屬：Human
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免疫原：Recombinant Human Claudin-18.2 protein
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Monoclonal
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抗體亞型：hIgG1
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純化方式：Affinity-chromatography
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克隆號：9C2
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, FC
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推薦稀釋比：
Application Recommended Dilution FC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
平均分:
實驗應用：IHC, FC, ELISA
樣品信息： 人胃黏膜細胞
稀釋比：1:100
產品評價： 我使用CSB-RA005498A1HU的抗體，進行ELISA和WB檢測人的細胞，WB檢測結果條帶較單一，檢測條帶大小與預期的一致，ELISA檢測EC50 為2.623-14.06 ng/mL。抗體特異性好，靈敏度高。
By 彭老師
實驗應用：FC
樣品信息：人來源細胞
稀釋比：1.100
產品評價： 正常流式過程。
By 付老師
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