vpx Antibody

Name: vpx Antibody
Brand: CUSABIO
SKU: CSB-PA320847HA01SHA

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說明書

產品詳情

產品名稱：

Rabbit anti-Simian immunodeficiency virus vpx Polyclonal antibody
Uniprot No.：

P11266
基因名：

vpx
別名：

vpx antibody; Protein Vpx antibody; Viral protein X antibody; X ORF protein antibody
宿主：

Rabbit
反應種屬：

Simian immunodeficiency virus
免疫原：

Recombinant Simian immunodeficiency virus Protein Vpx protein (1-112AA)
免疫原種屬：

Simian immunodeficiency virus

標記方式：

Non-conjugated

本頁面中的產品，vpx Antibody (CSB-PA320847HA01SHA)，的標記方式是Non-conjugated。對于vpx Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA320847HB01SHA	vpx Antibody, HRP conjugated	ELISA
FITC	CSB-PA320847HC01SHA	vpx Antibody, FITC conjugated
Biotin	CSB-PA320847HD01SHA	vpx Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription.
亞細胞定位：

Virion. Host nucleus.
蛋白家族：

Lentivirus VPX protein family

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