vpx Antibody, Biotin conjugated

^{Rare Species}

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Human immunodeficiency virus type 2 subtype A vpx Polyclonal antibody
Uniprot No.：

P06939
基因名：

vpx
別名：

vpxProtein Vpx antibody; Viral protein X antibody; X ORF protein antibody
宿主：

Rabbit
反應(yīng)種屬：

Human immunodeficiency virus type 2 subtype A
免疫原：

Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx protein (1-112AA)
免疫原種屬：

Human immunodeficiency virus type 2 subtype A
標(biāo)記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription.
亞細(xì)胞定位：

Virion. Host nucleus. Note=Nuclear just after virion uncoating, or if expressed in the absence of unprocessed GAG.
蛋白家族：

Lentivirus VPX protein family

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