rtcB Antibody, HRP conjugated

^{Rare Species}

說明書

產品詳情

產品名稱：

Rabbit anti-Escherichia coli rtcB Polyclonal antibody
Uniprot No.：

P46850
基因名：

rtcB
別名：

rtcB antibody; yhgL antibody; b3421 antibody; JW3384 antibody; RNA-splicing ligase RtcB antibody; EC 6.5.1.8 antibody; 3'-phosphate/5'-hydroxy nucleic acid ligase antibody
宿主：

Rabbit
反應種屬：

Escherichia coli
免疫原：

Recombinant Escherichia coli RNA-splicing ligase RtcB protein (1-408AA)
免疫原種屬：

Escherichia coli
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splicing 'dirty' DNA breaks, characterized by 3'-phosphate (or cyclic-phosphate) and 5'-hydroxy ends that cannot be sealed by classical DNA ligases.
基因功能參考文獻：
1. our findings not only provide a physiological function for the RNA ligase RtcB in bacteria but highlight the reversibility of ribosome heterogeneity, a crucial but hitherto undescribed concept for translational regulation. PMID: 27789694
2. Data show that RtcB seals broken RNAs with 3'-phosphate and 5'-OH ends. PMID: 22474365
3. RtcB, a novel RNA ligase, can catalyze tRNA splicing and HAC1 mRNA splicing in vivo PMID: 21757685
蛋白家族：

RtcB family
數據庫鏈接：

KEGG: ecj:JW3384

STRING: 316385.ECDH10B_3595

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