fliC Antibody

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中文名稱：

fliC兔多克隆抗體
貨號：

CSB-PA09734A0Rb
規格：

￥440
其他：

產品詳情
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產品詳情

產品描述：

fliC polyclonal antibody CSB-PA09734A0Rb was produced in the rabbit immunized by using the Recombinant Escherichia coli Flagellin protein (2-498AA) as the immunogen. The target protein fliC is the subunit protein which polymerizes to form the filaments of bacterial flagella. Studies indicate that toll-like receptor 5 (TLR5) specifically interacts with flagellin, and is useful as an analytical recognition element for low concentrations of flagellin. Flagellin subunit FliC function as adhesins to piglet epithelial cells invasion.
This Rabbit anti-Escherichia coli (strain K12) fliC Polyclonal antibody was tested in the ELISA. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It only reacts with the fliC proteins of Escherichia coli-origin and may be used to detect the endogenous levels of fliC protein.
產品名稱：

Rabbit anti-Escherichia coli fliC Polyclonal antibody
Uniprot No.：

P04949
基因名：

fliC
別名：

fliC antibody; flaF antibody; hag antibody; b1923 antibody; JW1908Flagellin antibody
宿主：

Rabbit
反應種屬：

Escherichia coli
免疫原：

Recombinant Escherichia coli Flagellin protein (2-498AA)
免疫原種屬：

Escherichia coli

標記方式：

Non-conjugated

本頁面中的產品，fliC Antibody (CSB-PA09734A0Rb)，的標記方式是Non-conjugated。對于fliC Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA09734B0Rb	fliC Antibody, HRP conjugated	ELISA
FITC	CSB-PA09734C0Rb	fliC Antibody, FITC conjugated
Biotin	CSB-PA09734D0Rb	fliC Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
基因功能參考文獻：
1. Studies indicate that toll-like receptor 5 (TLR5) specifically interacts with flagellin, and is useful as an analytical recognition element for low concentrations of flagellin. PMID: 24881544
2. Flagellin subunit FliC function as adhesins to piglet epithelial cells invasion. PMID: 23746569
3. Results showed a reproducible and clear cut classification with molecular polymorphism of gene rfb cluster and flagella gene fliC. PMID: 19656466
4. Flagellin in E. coli Nissle 1917 is the major stimulatory factor of human beta-defensin. PMID: 17283097
5. Relations between the diversity of the fliC gene conditioning flagellum protein in E. coli and the source of the strain origin are presented PMID: 17702465
6. Flagellin expression by uropathogenic Escherichia coli coincides with ascension of the ureters and colonization of the kidney. PMID: 17925449
7. This study demonstrated that infection of intestinal epithelial cells by A/E pathogens can trigger an array of proinflammatory responses from epithelial cells through both FliC-dependent and -independent pathways. PMID: 18227166
8. Insertion of Cys-derived thiol residues in the E. coli FliC protein increased Au(III) sorption and reduction onto the surface of the flagellar filament and resulted in the production of stabilized Au(0) nanoparticles of approximately 20-50 nm diameter. PMID: 18819156
9. Binding of a fliC(H7) mutant O157 strain to rectal epithelium was significantly reduced as was binding of the flagellated wild-type strain following incubation with H7-specific antibodies. PMID: 19016776
10. Increased IL-8 levels mainly depended on flagellin expression as fliC-negative EPEC did not elicit a significant IL-8 response despite increased mucosal colonization compared with wild-type EPEC. PMID: 19134113
11. FliC is secreted by the LEE-encoded type III secretion system and stimulates TLR5 signalling but does not confer motility. PMID: 19200386
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亞細胞定位：

Secreted. Bacterial flagellum.
蛋白家族：

Bacterial flagellin family
數據庫鏈接：

KEGG: ecj:JW1908

STRING: 316407.1736591

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