crr Antibody

^{Rare Species}

說明書

產(chǎn)品詳情

Uniprot No.：

P69783
基因名：

crr
別名：

PTS system glucose-specific EIIA component (EIIA-Glc) (EIII-Glc) (Glucose-specific phosphotransferase enzyme IIA component) (EC 2.7.1.199) crr gsr iex tgs treD b2417 JW2410
反應(yīng)種屬：

Escherichia coli (strain K12)
免疫原：

Recombinant Escherichia coli (strain K12) crr protein (12-67aa)
免疫原種屬：

Escherichia coli (strain K12)
標(biāo)記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Affinity-chromatography
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. The non-phosphorylated EIII-Glc is an inhibitor for uptake of certain sugars such as maltose, melibiose, lactose, and glycerol. Phosphorylated EIII-Glc, however, may be an activator for adenylate cyclase. It is an important regulatory protein for cell metabolism.
基因功能參考文獻(xiàn)：
1. Results suggest that the phosphoenolpyruvate hexose phosphotransferases PTS network serves as a global sensor of the sugar influx and also monitors the levels of several non-PTS compounds. PMID: 27557415
2. results of a detailed investigation of the role of EIIAGlc in CsrB/C decay; unphosphorylated EIIAGlc binds specifically to the EAL domain of CsrD and stimulates CsrB/C turnover PMID: 26507976
3. The data suggest a model of how the central regulatory protein EIIA(Glc) allosterically inhibits maltose uptake in E. coli. PMID: 23770568
亞細(xì)胞定位：

Cytoplasm.
數(shù)據(jù)庫鏈接：

KEGG: ecj:JW2410

STRING: 316385.ECDH10B_2582

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