ZXDC Antibody

說明書

產品詳情

Uniprot No.：

Q2QGD7
基因名：

ZXDC
別名：

ZXDC antibody; ZXDL antibody; Zinc finger protein ZXDC antibody; ZXD-like zinc finger protein antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Human ZXDC
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
基因功能參考文獻：
1. Data show that ZXDC1 is a regulator in the process of myeloid function and that ZXDC1 is responsible for Ccl2 gene de-repression by BCL6. PMID: 23954399
2. Role of ZXD proteins in regulating MHC II transcription. PMID: 19777325
3. ZXDC is an important regulator of both MHC class I and class II transcription PMID: 16600381
4. ZXDA and ZXDC form an important regulatory complex for MHC II gene transcription. PMID: 17493635
5. study found sumoylation does not appear to disrupt or modulate interaction of ZXDC with binding partners; sumoylation of ZXDC is required for full activity of transcriptional activation domain; study suggests sumoylation is an important regulator of ZXDC PMID: 17696781
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亞細胞定位：

Nucleus.
蛋白家族：

ZXD family
組織特異性：

Expressed at high levels in heart, kidney, liver and testis, at moderate levels in brain and stomach, and at low levels in lung, muscle, placenta, small intestine and spleen.
數據庫鏈接：

HGNC: 28160

OMIM: 615746

KEGG: hsa:79364

STRING: 9606.ENSP00000374359

UniGene: Hs.440049

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