ZRANB1 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ZRANB1 Polyclonal antibody
Uniprot No.：

Q9UGI0
基因名：

ZRANB1
別名：

DKFZp762P2216 antibody; hTrabid antibody; Trabid antibody; TRAF-binding protein domain antibody; Ubiquitin thioesterase ZRANB1 antibody; Zinc finger Ran-binding domain-containing protein 1 antibody; ZRAN1_HUMAN antibody; ZRANB1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Ubiquitin thioesterase ZRANB1 protein (111-397AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.
基因功能參考文獻：
1. Data show that the ankyrin-repeat ubiquitin-binding domain is crucial for TRABID efficiency and linkage specificity. PMID: 22157957
亞細胞定位：

Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm.
蛋白家族：

Peptidase C64 family
組織特異性：

Widely expressed.
數據庫鏈接：

HGNC: 18224

OMIM: 611749

KEGG: hsa:54764

STRING: 9606.ENSP00000352676

UniGene: Hs.595158

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