ZNF750 Antibody
-
中文名稱：ZNF750兔多克隆抗體
-
貨號：CSB-PA027012GA01HU
-
規(guī)格：￥3,900
-
其他：
產(chǎn)品詳情
-
Uniprot No.：
-
基因名：
-
別名：ZNF750 antibody; Zinc finger protein 750 antibody
-
宿主：Rabbit
-
反應(yīng)種屬：Human,Mouse
-
免疫原：Human ZNF750
-
免疫原種屬：Homo sapiens (Human)
-
抗體亞型：IgG
-
純化方式：Antigen Affinity purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
-
產(chǎn)品提供形式：Liquid
-
應(yīng)用范圍：ELISA,WB
-
Protocols：
-
儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能：Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression.
-
基因功能參考文獻(xiàn)：
- ZNF750 acts as a potential tumor suppressor gene, and regulates tumor microenvironment. PMID: 29890464
- The low expression of ZNF750 was significantly associated with a poor prognosis. PMID: 29216641
- ZNF750 expression predicts sensitivity to CRT and can be a biomarker that reliably predicts the response of ESCC to CRT. PMID: 28558382
- ZNF750 Mutation is associated with esophageal squamous cell carcinoma. PMID: 27749841
- Suggest no connection of ZNF750 variants with psoriasis or its subphenotypes. PMID: 24005976
- ZNF750 thus controls differentiation in concert with RCOR1 and CTBP1/2 by acting with either KDM1A to repress progenitor genes or KLF4 to induce differentiation genes. PMID: 25228645
- ZNF750 was specifically expressed in the epidermal suprabasal layers and its expression was augmented during differentiation, both in human skin and in-vitro, peaking in the granular layer. PMID: 22936986
- ZNF750 directly links a tissue-specifying factor, p63, to an effector of terminal differentiation, KLF4. PMID: 22364861
- Two haplotypes of ZNF750 and rare 5' regulatory variants of ZNF750 were found to be associated with psoriasis. PMID: 22185198
- ZNF750 mutations could contribute to psoriasis susceptibility. PMID: 18256691
顯示更多
收起更多
-
相關(guān)疾病：Seborrhea-like dermatitis with psoriasiform elements (SLDP)
-
亞細(xì)胞定位：Nucleus.
-
組織特異性：Expressed in the skin, prostate, lung, placenta and thymus, and at low level in T-cells. Not expressed in peripheral blood leukocytes, pancreas and brain. Clearly expressed in primary keratinocytes but not in fibroblasts.
-
數(shù)據(jù)庫鏈接：
Most popular with customers
-
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
-
