ZIP1 Antibody

^{Rare Species}

說明書

產品詳情

Uniprot No.：

P31111
基因名：

ZIP1
別名：

Synaptonemal complex protein ZIP1, ZIP1
反應種屬：

S. cerevisiae
免疫原：

Recombinant S. cerevisiae ZIP1 protein (603-875aa)
免疫原種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Affinity-chromatography
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Required for meiotic chromosome synapsis and cell cycle progression. May act as a molecular zipper to bring homologous chromosomes in close apposition. ZIP1 may encode the transverse filaments of the synaptonemal complex.
基因功能參考文獻：
1. We discuss a model in which central element proteins are core building blocks that stabilize the architecture of SC near Zip1's N termini PMID: 24098146
2. Data demonstrate that chromosomes are preloaded with Zip1p in a manner that may promote synapsis. PMID: 20375150
3. Different functions of Zip1 display differential sensitivities to changes in expression levels. PMID: 19714362
4. zip1 promotes the segregation of nonexchange chromosomes that are not tethered byp zip1 at centromeres. PMID: 20080752
5. description of a process in meiotic cells in which chromosomes become joined together in pairs at their centromeres independent of chromosomal homology; these centromeric interactions depend on the synaptonemal complex component Zip1 PMID: 15879219
6. The zip1-4LA defect in recombination is an indirect consequence of cell cycle arrest. PMID: 17435220
7. Zip1 and Hop1 Occur with Differential Hyperabundance Along Pachytene Chromosomes; Differential Hop1/Zip1 Hyperabundance Depends on Pch2 PMID: 18305165
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亞細胞定位：

Nucleus. Chromosome. Note=Synapsed meiotic chromosomes.
數據庫鏈接：

KEGG: sce:YDR285W

STRING: 4932.YDR285W

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