ZFP91 Antibody
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中文名稱：ZFP91兔多克隆抗體
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貨號：CSB-PA504466
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規格：￥1090
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圖片：
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Western Blot analysis of hepg2, NT28 cells using Antibody diluted at 500. Secondary antibody was diluted at 1:20000
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其他：
產品詳情
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Uniprot No.：
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基因名：ZFP91
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別名：ZFP91 antibody; ZNF757 antibody; FKSG11E3 ubiquitin-protein ligase ZFP91 antibody; EC 2.3.2.27 antibody; RING-type E3 ubiquitin transferase ZFP91 antibody; Zinc finger protein 757 antibody; Zinc finger protein 91 homolog antibody; Zfp-91 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthetic peptide from Human protein at AA range: 401-450
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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純化方式：The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB,ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-10000 ELISA 1:10000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis.
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基因功能參考文獻：
- lenalidomide induces the ubiquitination and degradation of ZFP91 PMID: 28530236
- Data show that NF-kappaB/p65 is required for the binding of zinc finger protein 91 (ZFP91) to the HIF-1alpha promoter and for the transcriptional activation of HIF-1alpha gene mediated by ZFP91. PMID: 27144516
- ZFP91 is overexpressed in prostate cancer. PMID: 27975057
- hHgher protein levels of ZFP91 in all cancer cell lines. PMID: 24272675
- These data clearly indicate that ZFP91 is a key regulator in LIGHT-induced activation of non-canonical NF-kappaB pathway in LTbetaR signaling. PMID: 20804734
- An atypical E3 ligase zinc finger protein 91 stabilizes and activates NF-kappaB-inducing kinase via Lys63-linked ubiquitination. PMID: 20682767
- likely to play an important role in cell proliferation and/or anti-apoptosis, and may serve as a molecular marker for AML PMID: 12738986
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亞細胞定位：Nucleus.
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蛋白家族：Krueppel C2H2-type zinc-finger protein family
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組織特異性：Expressed ubiquitously, particularly at high level in testis. Isoform 2 is testis specific.
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數據庫鏈接：
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