ZDHHC1 Antibody, Biotin conjugated

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) ZDHHC1 Polyclonal antibody
Uniprot No.：

Q8WTX9
基因名：

ZDHHC1
別名：

ZDHHC1; C16orf1; ZNF377; Palmitoyltransferase ZDHHC1; DHHC domain-containing cysteine-rich protein 1; Zinc finger DHHC domain-containing protein 1; DHHC-1; Zinc finger protein 377
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Probable palmitoyltransferase ZDHHC1 protein (283-389AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates. Has a palmitoyltransferase activity toward NCDN and regulates NCDN association with endosome membranes through this palmitoylation.; Has also a palmitoyltransferase activity-independent function in DNA virus-triggered and CGAS-mediated innate immune response. Functions as an activator of STING1 by promoting its cGAMP-induced oligomerization and the recruitment of downstream signaling components.
基因功能參考文獻(xiàn)：
1. In an expression screen for proteins that can activate the IFNB1 promoter, authors identified the ER-associated protein ZDHHC1 as a positive regulator of virus-triggered, MITA/STING-dependent immune signaling. PMID: 25299331
亞細(xì)胞定位：

Endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus.
蛋白家族：

DHHC palmitoyltransferase family
組織特異性：

Widely expressed with significant expression in heart, brain, placenta, lung, liver, kidney, testis, thymus and small intestine. Expressed at lower levels in adult pancreas and lung.
數(shù)據(jù)庫鏈接：

HGNC: 17916

KEGG: hsa:29800

STRING: 9606.ENSP00000340299

UniGene: Hs.624541

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