ZBED1 Antibody, Biotin conjugated
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中文名稱：ZBED1兔多克隆抗體, Biotin偶聯(lián)
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貨號(hào)：CSB-PA02715D0Rb
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) ZBED1 Polyclonal antibody
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Uniprot No.：
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基因名：ZBED1
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別名：Ac like transposable element antibody; ALTE antibody; BED type zinc finger domain containing protein 1 antibody; DNA replication related element binding factor antibody; dREF homolog antibody; hDREF antibody; KIAA0785 antibody; Putative Ac like transposon antibody; Putative Ac-like transposable element antibody; TRAMP antibody; ZBED1 antibody; ZBED1_HUMAN antibody; Zinc finger BED domain-containing protein 1 antibody; Zinc finger BED type containing 1 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Zinc finger BED domain-containing protein 1 protein (1-210AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase which sumoylates CHD3/Mi2-alpha, causing its release from DNA. This results in suppression of CHD3/Mi2-alpha transcription repression, increased recruitment of RNA polymerase II to gene promoters and positive regulation of transcription including H1-5 and ribosomal proteins such as: RPS6, RPL10A, and RPL12. The resulting increased transcriptional activity drives cell proliferation. Binds to 5'-TGTCG[CT]GA[CT]A-3' consensus sequences in gene promoters of ribosomal proteins.; (Microbial infection) Binds to human adenovirus gene promoters and contributes to transcriptional repression and virus growth inhibition during early stages of infection.
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基因功能參考文獻(xiàn)：
- These findings identify DREF as a novel adenovirus E1A C terminus binding partner and provide evidence supporting a role for DREF in viral replication. PMID: 25210186
- expression of hDREF/KIAA0785 may have a role in regulation of human genes related to cell proliferation PMID: 12663651
- self-association of hDREF via the hATC domain is necessary for its nuclear accumulation and DNA binding. PMID: 17209048
- hDREF is an important transcription factor for cell proliferation which plays roles in cell cycle-dependent regulation of a number of ribosomal protein genes PMID: 17220279
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亞細(xì)胞定位：Nucleus, PML body. Nucleus.; Nucleus, PML body.
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組織特異性：Ubiquitously expressed at low levels. Expression is highest in skeletal muscle, heart, spleen and placenta.
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數(shù)據(jù)庫鏈接：
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