WFDC1 Antibody
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中文名稱：WFDC1兔多克隆抗體
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貨號：CSB-PA026086GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：WFDC1
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別名：Prostate stromal protein ps20 antibody; PS20 antibody; ps20 growth inhibitor antibody; WAP four disulfide core domain 1 antibody; WAP four disulfide core domain 1 homolog antibody; WAP four-disulfide core domain protein 1 antibody; Wfdc1 antibody; WFDC1_HUMAN antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human WFDC1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Has growth inhibitory activity.
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基因功能參考文獻：
- Prostrate stromal 20 overexpression upregulates expression of cyclooxygenase-2 (COX-2) in LNCaP and WPMY-1 cells, and induces expression of a growth-suppressive phenotype, which inhibits proliferation of PCa cells by ps20-expressing WPMY-1 conditioned media. PMID: 27115470
- HIV-1 virus transfer among primary CD4+ T-lymphocytes was promoted by ectopic ps20 expression or by exogenous addition of recombinant ps20. PMID: 21545747
- results suggest a minor role, if any, of WFDC1 in hepatocarcinogenesis PMID: 12032731
- WFDC1/ps20 is down regulated but not frequently mutated in prostate cancer. It is expressed predominantly in the normal prostatic stroma. It might play a role in the maintenance of the normal extra cellular matrix milieu in the prostate. PMID: 15305342
- ps20 promoted HIV entry via fusion and augmented CD54 integrin expression PMID: 17942534
- data suggest an important role for WFDC1 in inhibiting proliferation of both tumors and senescent cells. Finally, we suggest that the downregulation of WFDC1 might serve as a biomarker for cellular transformation PMID: 18842679
- suggests that the tumor suppressive function of WFDC1 may be partially a result of up-regulated Dkk1 gene expression, which is known to be a potent inhibitor of the Wnt signaling pathway PMID: 19488830
- our data suggest an important role for WFDC1 in inhibiting proliferation of both tumors and senescent cells PMID: 18842679
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亞細胞定位：Secreted.
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數據庫鏈接：
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