WDR60 Antibody

中文名稱：

WDR60兔多克隆抗體
貨號：

CSB-PA845154HA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA845154HA01HU at dilution of 1:100

Immunofluorescent analysis of HepG2 cells using CSB-PA845154HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產品詳情

標記方式：

Non-conjugated

本頁面中的產品，WDR60 Antibody (CSB-PA845154HA01HU)，的標記方式是Non-conjugated。對于WDR60 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA845154HB01HU	WDR60 Antibody, HRP conjugated	ELISA
FITC	CSB-PA845154HC01HU	WDR60 Antibody, FITC conjugated
Biotin	CSB-PA845154HD01HU	WDR60 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I1 plays a major role in retrograde ciliary protein trafficking in cilia and flagella. Requires also to maintain a functional transition zone.
基因功能參考文獻：
1. exome analysis allowed to identify mutations not previously reported in the DYNC2H1 (MIM 603297) and WDR60 (MIM 615462) genes, both codifying for ciliary intraflagellar transport components whose mutations are known to cause Jeune syndrome PMID: 26874042
2. These findings show that WDR60 mutations can cause skeletal ciliopathies and suggest a role for WDR60 in ciliogenesis. PMID: 23910462
相關疾病：

Short-rib thoracic dysplasia 8 with or without polydactyly (SRTD8)
亞細胞定位：

Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
組織特異性：

Expressed in chondrocytes (at protein level).
數據庫鏈接：

HGNC: 21862

OMIM: 615462

KEGG: hsa:55112

STRING: 9606.ENSP00000384290

UniGene: Hs.389945

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