WDFY4 Antibody, Biotin conjugated
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中文名稱：WDFY4兔多克隆抗體, Biotin偶聯(lián)
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貨號(hào)：CSB-PA747798LD01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) WDFY4 Polyclonal antibody
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Uniprot No.：
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基因名：WDFY4
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別名：WDFY4 antibody; C10orf64 antibody; KIAA1607WD repeat- and FYVE domain-containing protein 4 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human WD repeat- and FYVE domain-containing protein 4 protein (1-322AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Biotin
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克隆類(lèi)型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點(diǎn)詳情
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功能：Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.
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基因功能參考文獻(xiàn)：
- A significantly increased risk for RA associated with the WDFY4 rs7097397 AG genotype. PMID: 24549174
- rs877819 SNP in WDFY4 may be associated with systemic lupus erythematosus by reduced binding of YY1 and downregulating WDFY4 expression. PMID: 22972472
- Genetic variants in ETS1 and WDFY4 were found to be associated with systemic lupus erythematosus, in the Asian population studied. PMID: 20169177
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亞細(xì)胞定位：Early endosome. Endoplasmic reticulum.
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數(shù)據(jù)庫(kù)鏈接：
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